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Light treatment of infants with hyperbilirubinaemia - optimalization and dosimetry; Optimalisering og dosimetri ved lysbehandling av nyfoedte med hyperbilirubinemi

Technical Report:

Abstract

This report deals with certain aspects of phototherapy of infants with hyperbilirubinaemia. The first part of the report concerns light measurement at different distances from a phototherapy unit equipped with eight fluorescent tubes. At the actual distance of treatment, there was a considerable lack of homogeneity with the largest irradiance below the center of the unit. The second part of the report is a study of the formation of different isomers of bilirubin detected by use of HPLC. The research was mainly done in vitro by irradiation of bilirubin solutions. Three different fluorescent tubes were used which emitted white, blue and green light. The green light was most efficient in producing Z-lumirubin, which is considered as the main isomer responsible for excretion of bilirubin from infants. Green light may be safer to use than blue light and may in the future be the wavelength of choice in phototherapy. 43 refs., 50 figs.
Authors:
Publication Date:
Dec 31, 1991
Product Type:
Technical Report
Report Number:
SIS-1991:7
Reference Number:
SCA: 550603; PA: AIX-23:008222; SN: 92000619623
Resource Relation:
Other Information: PBD: 1991
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BILIRUBIN; ISOMERIZATION; JAUNDICE; RADIOTHERAPY; DOSIMETRY; INFANTS; OPTIMIZATION; PHOTOCHEMISTRY; SIDE EFFECTS; VISIBLE RADIATION; 550603; EXTERNAL RADIATION IN THERAPY
OSTI ID:
10104107
Research Organizations:
Statens Inst. for Straalehygiene, Oslo (Norway)
Country of Origin:
Norway
Language:
Norwegian
Other Identifying Numbers:
Other: ON: DE92612808; TRN: NO9100131008222
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
NWN
Size:
86 p.
Announcement Date:
Jun 30, 2005

Technical Report:

Citation Formats

Amundsen, I. Light treatment of infants with hyperbilirubinaemia - optimalization and dosimetry; Optimalisering og dosimetri ved lysbehandling av nyfoedte med hyperbilirubinemi. Norway: N. p., 1991. Web.
Amundsen, I. Light treatment of infants with hyperbilirubinaemia - optimalization and dosimetry; Optimalisering og dosimetri ved lysbehandling av nyfoedte med hyperbilirubinemi. Norway.
Amundsen, I. 1991. "Light treatment of infants with hyperbilirubinaemia - optimalization and dosimetry; Optimalisering og dosimetri ved lysbehandling av nyfoedte med hyperbilirubinemi." Norway.
@misc{etde_10104107,
title = {Light treatment of infants with hyperbilirubinaemia - optimalization and dosimetry; Optimalisering og dosimetri ved lysbehandling av nyfoedte med hyperbilirubinemi}
author = {Amundsen, I}
abstractNote = {This report deals with certain aspects of phototherapy of infants with hyperbilirubinaemia. The first part of the report concerns light measurement at different distances from a phototherapy unit equipped with eight fluorescent tubes. At the actual distance of treatment, there was a considerable lack of homogeneity with the largest irradiance below the center of the unit. The second part of the report is a study of the formation of different isomers of bilirubin detected by use of HPLC. The research was mainly done in vitro by irradiation of bilirubin solutions. Three different fluorescent tubes were used which emitted white, blue and green light. The green light was most efficient in producing Z-lumirubin, which is considered as the main isomer responsible for excretion of bilirubin from infants. Green light may be safer to use than blue light and may in the future be the wavelength of choice in phototherapy. 43 refs., 50 figs.}
place = {Norway}
year = {1991}
month = {Dec}
}