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Monoclonal antibody as radiopharmaceutical

Abstract

The purification of anti-CEA monoclonal antibody 4C11 belonging to IgG sub(2a) subclass from mouse ascitis, donated by Ludwig Institute, Brazil was developed. The fragmentation of purified IgG sub(2a) by pepsin digestion and analytical studies by polyacrilamide gel electrophoresis in the presence of sodium dodecyl sulfate (SDS-PAGE) were done as preliminary assessment for their specific application in immunoscintigraphy. (author).
Publication Date:
Jun 01, 1991
Product Type:
Technical Report
Report Number:
IPEN-PUB-339
Reference Number:
SCA: 400703; PA: AIX-23:004336; SN: 91000614739
Resource Relation:
Other Information: PBD: Jun 1991
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; MONOCLONAL ANTIBODIES; IMMUNOLOGY; RADIOPHARMACEUTICALS; ELECTROPHORESIS; SCINTISCANNING; 400703; RADIOISOTOPE PRODUCTION
OSTI ID:
10102413
Research Organizations:
Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil)
Country of Origin:
Brazil
Language:
English
Other Identifying Numbers:
Other: ON: DE92611339; TRN: BR9127906004336
Availability:
OSTI; NTIS (US Sales Only); INIS
Submitting Site:
INIS
Size:
16 p.
Announcement Date:
Jun 30, 2005

Citation Formats

Toledo e Souza, I.T. de, Okada, H, and Silva, C P.G. da. Monoclonal antibody as radiopharmaceutical. Brazil: N. p., 1991. Web.
Toledo e Souza, I.T. de, Okada, H, & Silva, C P.G. da. Monoclonal antibody as radiopharmaceutical. Brazil.
Toledo e Souza, I.T. de, Okada, H, and Silva, C P.G. da. 1991. "Monoclonal antibody as radiopharmaceutical." Brazil.
@misc{etde_10102413,
title = {Monoclonal antibody as radiopharmaceutical}
author = {Toledo e Souza, I.T. de, Okada, H, and Silva, C P.G. da}
abstractNote = {The purification of anti-CEA monoclonal antibody 4C11 belonging to IgG sub(2a) subclass from mouse ascitis, donated by Ludwig Institute, Brazil was developed. The fragmentation of purified IgG sub(2a) by pepsin digestion and analytical studies by polyacrilamide gel electrophoresis in the presence of sodium dodecyl sulfate (SDS-PAGE) were done as preliminary assessment for their specific application in immunoscintigraphy. (author).}
place = {Brazil}
year = {1991}
month = {Jun}
}