"TITLE","AUTHORS","SUBJECT","SUBJECT_RELATED","DESCRIPTION","PUBLISHER","AVAILABILITY","RESEARCH_ORG","SPONSORING_ORG","PUBLICATION_COUNTRY","PUBLICATION_DATE","CONTRIBUTING_ORGS","LANGUAGE","RESOURCE_TYPE","TYPE_QUALIFIER","JOURNAL_ISSUE","JOURNAL_VOLUME","RELATION","COVERAGE","FORMAT","IDENTIFIER","REPORT_NUMBER","DOE_CONTRACT_NUMBER","OTHER_IDENTIFIER","DOI","RIGHTS","ENTRY_DATE","OSTI_IDENTIFIER","PURL_URL" "Leading research on artificial techniques controlling cellular function; Saibo zoshoku seigyo gijutsu no sendo kenkyu","NONE","55 BIOLOGY AND MEDICINE, BASIC STUDIES; 29 ENERGY PLANNING AND POLICY; GROWTH; CELL DIFFERENTIATION; CELL PROLIFERATION; ANIMAL CELLS; PLANT CELLS; CONTROL SYSTEMS; BIOTECHNOLOGY; GROWTH FACTORS; PROTEIN ENGINEERING; MATERIALS; ARTIFICIAL INTELLIGENCE; BIOREACTORS; CELL KILLING; AGING; IN VITRO; IN VIVO; ARTIFICIAL ORGANS","","Advanced research and its applicability were surveyed to apply the advanced functional cells to industry. The basic target was set to develop, produce, control and utilize the functional cells, such as intelligent materials and self-regulation bioreactors. The regulation factors regarding apotosis, which is a process of cell suicide programmed within the cell itself of multicellular organisms, cell cycle and aging/ageless were investigated. Furthermore, the function of regulatory factors was investigated at the protein level. Injection of factors regulating cellular function and tissue engineering required for the regulation of cell proliferation were investigated. Tissue engineering is considered to be the intracellular regulation by gene transduction and the extracellular regulation by culture methods, such as coculture. Analysis methods for cell proliferation and function of living cells were investigated using the probes recognizing molecular structure. Novel biomaterials, artificial organ systems, cellular therapy and useful materials were investigated for utilizing the regulation techniques of cell proliferation. 425 refs., 85 figs., 9 tabs.","","Available from Office of Scientific and Technical Information, P.O.Box 1000, Oak Ridge Tennessee 37831, USA; OSTI as DE97717512","New Energy and Industrial Technology Development Organization, Tokyo (Japan)","","Japan","1996-03-01","","Japanese","Technical Report","","","","Other Information: PBD: Mar 1996","","Medium: ED; Size: 277 p.","ON: DE97717512","NEDO-PR-95010","","Other: ON: DE97717512; TRN: 96:820116","https://doi.org/","","2018-04-10","402298","https://www.osti.gov/etdeweb/servlets/purl/402298"