{
  "date" : "2013-08-15",
  "identifier_doecontract" : "",
  "subject" : "75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY; COATINGS; FIELD EMISSION; FOURIER TRANSFORM SPECTROMETERS; IMPLANTS; IN VITRO; INFRARED SPECTRA; LAYERS; MINERALIZATION; PHOTOCHEMISTRY; REFRACTION; REGENERATION; SCANNING ELECTRON MICROSCOPY; SKELETON; SUBSTRATES; SURFACES; TITANIUM; X-RAY DIFFRACTION; X-RAY PHOTOELECTRON SPECTROSCOPY; X-RAY SPECTRA; NANOPARTICLES",
  "description" : "Immobilizing organic–inorganic hybrid composites onto the implant surface is a promising strategy to improve host acceptance of the implant. The objective of this present study was to obtain a unique macroporous titanium-surface with the organic–mineral composite coatings consisting of gelatin methacrylate hydrogel (GelMA) and hydroxyapatite (HA). A 3-(trimethoxysilyl) propyl methacrylate (TMSPMA) layer was first coated onto the titanium surface, and surface was then covalently functionalized with GelMA using a photochemical method. Mineralization of the GelMA coating on the titanium surface was subsequently carried out by a biomimetic method. After 3-day mineralization, a large number of mineral phases comprising spherical amorphous nanoparticles were found randomly deposited inside GelMA matrix. The resulting mineralized hydrogel composites exhibited a unique rough surface of macroporous structure. The structure of the prepared GelMA/HA composite coating was studied by field emission scanning electron microscopy (FESEM), energy dispersive X-ray spectra (EDS), attenuated total refraction Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). Water contact angle measurement revealed the hydrophilicity properties of composite coatings. GelMA/HA on titanium after the TMSPMA treatment is very stable when tested in vitro with a PBS solution at 37 °C, due to the role of TMSPMA as a molecular bridge. It was expected that the macroporous GelMA/HA composite coatings might potentially promote and accelerate titanium (Ti)-based implants osseointegration for bone repair and regeneration.",
  "language" : "English",
  "identifier_report" : "",
  "publisher_sponsor" : "",
  "publisher_country" : "Netherlands",
  "source" : "NLN",
  "purl" : "",
  "title" : "Biomimetically-mineralized composite coatings on titanium functionalized with gelatin methacrylate hydrogels",
  "type" : "Journal Article",
  "subject_related" : "NANOPARTICLES",
  "relation" : "Journal Name: Applied Surface Science; Journal Volume: 279; Other Information: Copyright (c) 2013 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)",
  "entry_date" : "2015-01-19",
  "subject_list" : [ "75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY", "COATINGS", "FIELD EMISSION", "FOURIER TRANSFORM SPECTROMETERS", "IMPLANTS", "IN VITRO", "INFRARED SPECTRA", "LAYERS", "MINERALIZATION", "PHOTOCHEMISTRY", "REFRACTION", "REGENERATION", "SCANNING ELECTRON MICROSCOPY", "SKELETON", "SUBSTRATES", "SURFACES", "TITANIUM", "X-RAY DIFFRACTION", "X-RAY PHOTOELECTRON SPECTROSCOPY", "X-RAY SPECTRA", "NANOPARTICLES" ],
  "publisher_availability" : "Available from http://dx.doi.org/10.1016/j.apsusc.2013.04.088",
  "rights" : "",
  "announced_date" : "2015-01-19",
  "type_qualifier" : "",
  "has_fulltext" : false,
  "coverage" : "",
  "identifier" : "PII: S0169-4332(13)00792-7",
  "journal_volume" : "279",
  "creator" : "Tan, Guoxin [School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006 (China)]; Zhou, Lei [School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006 (China)]; Ning, Chengyun [College of Materials Science and Technology, South China University of Technology, Guangzhou, 510641 (China)]; Tan, Ying [School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006 (China)]; Ni, Guoxin [Department of Orthopedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515 (China)]; Liao, Jingwen; Yu, Peng; Chen, Xiaofeng [College of Materials Science and Technology, South China University of Technology, Guangzhou, 510641 (China)]",
  "site_ownership_code" : "NLN",
  "osti_id" : "22297177",
  "journal_issue" : "",
  "resource_type" : "JOUR",
  "format" : "Medium: X; Size: page(s) 293-299",
  "journal_name" : [ ],
  "contributing_organizations" : "",
  "citation_location" : "https://www.osti.gov/etdeweb/biblio/22297177",
  "publication_year" : 2013,
  "subject_list_commas" : "75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND SUPERFLUIDITY, COATINGS, FIELD EMISSION, FOURIER TRANSFORM SPECTROMETERS, IMPLANTS, IN VITRO, INFRARED SPECTRA, LAYERS, MINERALIZATION, PHOTOCHEMISTRY, REFRACTION, REGENERATION, SCANNING ELECTRON MICROSCOPY, SKELETON, SUBSTRATES, SURFACES, TITANIUM, X-RAY DIFFRACTION, X-RAY PHOTOELECTRON SPECTROSCOPY, X-RAY SPECTRA, NANOPARTICLES",
  "publisher" : "",
  "identifier_other" : "Journal ID: ISSN 0169-4332; CODEN: ASUSEE; Other: PII: S0169-4332(13)00792-7; TRN: NL14R0841003348",
  "publisher_research" : "",
  "creators_list" : [ "Tan, Guoxin [School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006 (China)]", "Zhou, Lei [School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006 (China)]", "Ning, Chengyun [College of Materials Science and Technology, South China University of Technology, Guangzhou, 510641 (China)]", "Tan, Ying [School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, 510006 (China)]", "Ni, Guoxin [Department of Orthopedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515 (China)]", "Liao, Jingwen", "Yu, Peng", "Chen, Xiaofeng [College of Materials Science and Technology, South China University of Technology, Guangzhou, 510641 (China)]" ],
  "doi" : "https://doi.org/10.1016/J.APSUSC.2013.04.088"
}