{
  "date" : "2012-09-15",
  "identifier_doecontract" : "",
  "subject" : "62 RADIOLOGY AND NUCLEAR MEDICINE; IN VIVO; INJURIES; NMR IMAGING; RABBITS; REGENERATION; SCIATIC NERVE; STEM CELLS",
  "description" : "Objective: To assess the continuous process of nerve regeneration in acute peripheral nerve traction injury treated with mesenchymal stem cells (MSCs) transplantation using MRI. Materials and methods: 1 week after acute nerve traction injury was established in the sciatic nerve of 48 New Zealand white rabbits, 5 × 10{sup 5} MSCs and vehicle alone were grafted to the acutely distracted sciatic nerves each in 24 animals. Serial MRI and T1 and T2 measurements of the injured nerves were performed with a 1.5-T scanner and functional recovery was recorded over a 10-week follow-up period, with histological assessments performed at regular intervals. Results: Compared with vehicle control, nerves grafted with MSCs had better functional recovery and showed improved nerve regeneration, with a sustained increase of T1 and T2 values during the phase of regeneration. Conclusion: MRI could be used to monitor the enhanced nerve regeneration in acute peripheral nerve traction injury treated with MSC transplantation, reflected by a prolonged increase in T1 and T2 values of the injured nerves.",
  "language" : "English",
  "identifier_report" : "",
  "publisher_sponsor" : "",
  "publisher_country" : "Netherlands",
  "source" : "NLN",
  "purl" : "",
  "title" : "In vivo MRI monitoring nerve regeneration of acute peripheral nerve traction injury following mesenchymal stem cell transplantation",
  "type" : "Journal Article",
  "subject_related" : "",
  "relation" : "Journal Name: European Journal of Radiology; Journal Volume: 81; Journal Issue: 9; Other Information: Copyright (c) 2011 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA)",
  "entry_date" : "2014-10-06",
  "subject_list" : [ "62 RADIOLOGY AND NUCLEAR MEDICINE", "IN VIVO", "INJURIES", "NMR IMAGING", "RABBITS", "REGENERATION", "SCIATIC NERVE", "STEM CELLS" ],
  "publisher_availability" : "Available from http://dx.doi.org/10.1016/j.ejrad.2011.06.050",
  "rights" : "",
  "announced_date" : "2014-10-06",
  "type_qualifier" : "",
  "has_fulltext" : false,
  "coverage" : "",
  "identifier" : "PII: S0720-048X(11)00591-2",
  "journal_volume" : "81",
  "creator" : "Duan, Xiao-Hui [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Cheng, Li-Na [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Zhang, Fang [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Liu, Jun [Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Guo, Ruo-Mi [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Zhong, Xiao-Mei [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Wen, Xue-Hua [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]; Shen, Jun [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]",
  "site_ownership_code" : "NLN",
  "osti_id" : "22267518",
  "journal_issue" : "9",
  "resource_type" : "JOUR",
  "format" : "Medium: X; Size: page(s) 2154-2160",
  "journal_name" : [ ],
  "contributing_organizations" : "",
  "citation_location" : "https://www.osti.gov/etdeweb/biblio/22267518",
  "publication_year" : 2012,
  "subject_list_commas" : "62 RADIOLOGY AND NUCLEAR MEDICINE, IN VIVO, INJURIES, NMR IMAGING, RABBITS, REGENERATION, SCIATIC NERVE, STEM CELLS",
  "publisher" : "",
  "identifier_other" : "Journal ID: ISSN 0720-048X; CODEN: EJRADR; Other: PII: S0720-048X(11)00591-2; TRN: NL13R1356088749",
  "publisher_research" : "",
  "creators_list" : [ "Duan, Xiao-Hui [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Cheng, Li-Na [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Zhang, Fang [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Liu, Jun [Department of Neurology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Guo, Ruo-Mi [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Zhong, Xiao-Mei [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Wen, Xue-Hua [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]", "Shen, Jun [Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107 Yanjiang Road West, Guangzhou 510120, Guangdong (China)]" ],
  "doi" : "https://doi.org/10.1016/J.EJRAD.2011.06.050"
}