TY - RPRT TI - Radioaerosol lung scanning in chronic obstructive pulmonary disease (COPD) and related disorders AB - As a coordinated research project of the International Atomic Energy Agency (IAEA), a multicentre joint study on radioaerosol lung scan using the BARC nebulizer has prospectively been carried out during 1988-1992 with the participation of 10 member countries in Asia [Bangladesh, China, India, Indonesia, Japan, Korea, Pakistan, Philippines, Singapore and Thailand]. The study was designed so that it would primarily cover chronic obstructive pulmonary disease (COPD) and the other related and common pulmonary diseases. The study also included normal controls and asymptomatic smokers. The purposes of this presentation are three fold: firstly, to document the usefulness of the nebulizer and the validity of user's protocol in imaging COPD and other lung diseases; secondly, to discuss scan features of the individual COPD and other disorders studied and thirdly, to correlate scan alterations with radiographic findings. Before proceeding with a systematic analysis of aerosol scan patterns in the disease groups, we documented normal pattern. The next step was the assessment of scan features in those who had been smoking for more than several years but had no symptoms or signs referable to airways. The lung diseases we analyzed included COPD [emphysema, chronic bronchitis, asthma and bronchiectasis], bronchial obstruction, compensatory overinflation and other common lung diseases such as lobar pneumonia, tuberculosis, interstitial fibrosis, diffuse panbronchiolitis, lung edema and primary and metastatic lung cancers. Lung embolism, inhalation bums and glue-sniffer's lung are separately discussed by Dr. Sundram of Singapore elsewhere in this book. The larger portion of this chapter is allocated to the discussion of COPD with a special effort made in sorting out differential scan features. Diagnostic criteria in individual COPD were defined for each category of disease and basic clinical symptoms and signs and pertinent laboratory data as well as radiographic manifestations are described. In addition, where possible COPD was classified into clinical subgroups according to the severity of disease for the purpose of testing whether any quantitative differences in their scan features exist. AU - "Bahk, Yong Whee [Departments of Radiology and Nuclear Medicine, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul (Korea, Republic of)]" AU - "Chung, Soo Kyo [Department of Nuclear Medicine, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul (Korea, Republic of)]" KW - "62 RADIOLOGY AND NUCLEAR MEDICINE" KW - "BIOLOGICAL LOCALIZATION" KW - "COMPUTERIZED TOMOGRAPHY" KW - "DIAGNOSTIC TECHNIQUES" KW - "IMAGE PROCESSING" KW - "INHALATION" KW - "LUNGS" KW - "RADIOACTIVE AEROSOLS" KW - "RADIOISOTOPE SCANNERS" KW - "RESPIRATORY SYSTEM DISEASES" KW - "TOBACCO SMOKES" DO - https://doi.org/ UR - https://www.osti.gov/etdeweb/servlets/purl/20137446 PB - CY - IAEA PY - 1994 DA - 1994-07-01 LA - English J2 - [] VL - C1 - International Atomic Energy Agency, Division of Human Health, Nuclear Medicine Section, Vienna (Austria) C2 - C3 - INIS-XA-292 C4 - C5 - Available from INIS in electronic form L3 - Other Information: 29 refs, 49 figs; PBD: 1994; Related Information: In: Radioaerosol imaging of the lung. An IAEA [CRP] group study, by Yong Whee Bahk [Departments of Radiology and Nuclear Medicine, Kangnam St. Mary's Hospital, Catholic University Medical College, Seoul (Korea, Republic of)]; Isawa, Toyoharu [Tohoku University Research Institute for Chest Disease and Cancer, Sendai (Japan)] [eds.], 155 pages. ER -