Safe biodegradable fluorescent particles
Abstract
A human-safe fluorescence particle that can be used for fluorescence detection instruments or act as a safe simulant for mimicking the fluorescence properties of microorganisms. The particle comprises a non-biological carrier and natural fluorophores encapsulated in the non-biological carrier. By doping biodegradable-polymer drug delivery microspheres with natural or synthetic fluorophores, the desired fluorescence can be attained or biological organisms can be simulated without the associated risks and logistical difficulties of live microorganisms.
- Inventors:
-
- Berkeley, CA
- Alamo, CA
- Santa Clara, CA
- Dublin, CA
- Oakland, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 991732
- Patent Number(s):
- 7781224
- Application Number:
- 11/502,301
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Martin, Sue I, Fergenson, David P, Srivastava, Abneesh, Bogan, Michael J, Riot, Vincent J, and Frank, Matthias. Safe biodegradable fluorescent particles. United States: N. p., 2010.
Web.
Martin, Sue I, Fergenson, David P, Srivastava, Abneesh, Bogan, Michael J, Riot, Vincent J, & Frank, Matthias. Safe biodegradable fluorescent particles. United States.
Martin, Sue I, Fergenson, David P, Srivastava, Abneesh, Bogan, Michael J, Riot, Vincent J, and Frank, Matthias. Tue .
"Safe biodegradable fluorescent particles". United States. https://www.osti.gov/servlets/purl/991732.
@article{osti_991732,
title = {Safe biodegradable fluorescent particles},
author = {Martin, Sue I and Fergenson, David P and Srivastava, Abneesh and Bogan, Michael J and Riot, Vincent J and Frank, Matthias},
abstractNote = {A human-safe fluorescence particle that can be used for fluorescence detection instruments or act as a safe simulant for mimicking the fluorescence properties of microorganisms. The particle comprises a non-biological carrier and natural fluorophores encapsulated in the non-biological carrier. By doping biodegradable-polymer drug delivery microspheres with natural or synthetic fluorophores, the desired fluorescence can be attained or biological organisms can be simulated without the associated risks and logistical difficulties of live microorganisms.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 24 00:00:00 EDT 2010},
month = {Tue Aug 24 00:00:00 EDT 2010}
}
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