Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream
Abstract
A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are provided for spatially confining the material in a focusing element. The device is also adapted for segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.
- Inventors:
-
- Knoxville, TN
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 984952
- Patent Number(s):
- 7422669
- Application Number:
- 10/758,718
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Jacobson, Stephen C, and Ramsey, J Michael. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream. United States: N. p., 2008.
Web.
Jacobson, Stephen C, & Ramsey, J Michael. Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream. United States.
Jacobson, Stephen C, and Ramsey, J Michael. Tue .
"Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream". United States. https://www.osti.gov/servlets/purl/984952.
@article{osti_984952,
title = {Microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream},
author = {Jacobson, Stephen C and Ramsey, J Michael},
abstractNote = {A microfluidic device and method for forming and dispensing minute volume segments of a material are described. In accordance with the present invention, a microfluidic device and method are provided for spatially confining the material in a focusing element. The device is also adapted for segmenting the confined material into minute volume segments, and dispensing a volume segment to a waste or collection channel. The device further includes means for driving the respective streams of sample and focusing fluids through respective channels into a chamber, such that the focusing fluid streams spatially confine the sample material. The device may also include additional means for driving a minute volume segment of the spatially confined sample material into a collection channel in fluid communication with the waste reservoir.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 09 00:00:00 EDT 2008},
month = {Tue Sep 09 00:00:00 EDT 2008}
}
Works referenced in this record:
Electrokinetic Flow in a Narrow Cylindrical Capillary
journal, November 1965
- Rice, C. L.; Whitehead, R.
- The Journal of Physical Chemistry, Vol. 69, Issue 11
Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip
journal, August 1993
- Harrison, D. J.; Fluri, K.; Seiler, K.
- Science, Vol. 261, Issue 5123
Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane)
journal, October 1998
- Duffy, David C.; McDonald, J. Cooper; Schueller, Olivier J. A.
- Analytical Chemistry, Vol. 70, Issue 23, p. 4974-4984