Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis
Abstract
Described herein is the identification of nucleotide sequences specific to Francisella tularensis that serves as a marker or signature for identification of this bacterium. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.
- Inventors:
-
- Tracy, CA
- San Mateo, CA
- Berkeley, CA
- Livermore, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 961572
- Patent Number(s):
- 7494778
- Application Number:
- 11/644,669
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
McCready, Paula M, Radnedge, Lyndsay, Andersen, Gary L, Ott, Linda L, Slezak, Thomas R, Kuczmarski, Thomas A, and Vitalis, Elizabeth A. Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis. United States: N. p., 2009.
Web.
McCready, Paula M, Radnedge, Lyndsay, Andersen, Gary L, Ott, Linda L, Slezak, Thomas R, Kuczmarski, Thomas A, & Vitalis, Elizabeth A. Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis. United States.
McCready, Paula M, Radnedge, Lyndsay, Andersen, Gary L, Ott, Linda L, Slezak, Thomas R, Kuczmarski, Thomas A, and Vitalis, Elizabeth A. Tue .
"Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis". United States. https://www.osti.gov/servlets/purl/961572.
@article{osti_961572,
title = {Nucleotide sequences specific to Francisella tularensis and methods for the detection of Francisella tularensis},
author = {McCready, Paula M and Radnedge, Lyndsay and Andersen, Gary L and Ott, Linda L and Slezak, Thomas R and Kuczmarski, Thomas A and Vitalis, Elizabeth A},
abstractNote = {Described herein is the identification of nucleotide sequences specific to Francisella tularensis that serves as a marker or signature for identification of this bacterium. In addition, forward and reverse primers and hybridization probes derived from these nucleotide sequences that are used in nucleotide detection methods to detect the presence of the bacterium are disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 24 00:00:00 EST 2009},
month = {Tue Feb 24 00:00:00 EST 2009}
}
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Works referenced in this record:
Detection of Francisella tularensis in blood by polymerase chain reaction.
journal, January 1993
- Long, G. W.; Oprandy, J. J.; Narayanan, R. B.
- Journal of Clinical Microbiology, Vol. 31, Issue 1
Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4
journal, October 2001
- Prior, R. G.; Klasson, L.; Larsson, P.
- Journal of Applied Microbiology, Vol. 91, Issue 4
Sequencing of the Francisella tularensis Strain Schu 4 Genome Reveals the Shikimate and Purine Metabolic Pathways, Targets for the Construction of a Rationally Attenuated Auxotrophic Vaccine
journal, March 2000
- Karlsson, Jan; Prior, Richard G.; Williams, Kerstin
- Microbial & Comparative Genomics, Vol. 5, Issue 1