Apparatus and method for monitoring breath acetone and diabetic diagnostics
Abstract
An apparatus and method for monitoring diabetes through breath acetone detection and quantitation employs a microplasma source in combination with a spectrometer. The microplasma source provides sufficient energy to produce excited acetone fragments from the breath gas that emit light. The emitted light is sent to the spectrometer, which generates an emission spectrum that is used to detect and quantify acetone in the breath gas.
- Inventors:
-
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 943439
- Patent Number(s):
- 7417730
- Application Number:
- 11/395,733
- Assignee:
- Los Alamos National Security, LLC (Los Alamos, NM)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01J - MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Duan, Yixiang, and Cao, Wenqing. Apparatus and method for monitoring breath acetone and diabetic diagnostics. United States: N. p., 2008.
Web.
Duan, Yixiang, & Cao, Wenqing. Apparatus and method for monitoring breath acetone and diabetic diagnostics. United States.
Duan, Yixiang, and Cao, Wenqing. Tue .
"Apparatus and method for monitoring breath acetone and diabetic diagnostics". United States. https://www.osti.gov/servlets/purl/943439.
@article{osti_943439,
title = {Apparatus and method for monitoring breath acetone and diabetic diagnostics},
author = {Duan, Yixiang and Cao, Wenqing},
abstractNote = {An apparatus and method for monitoring diabetes through breath acetone detection and quantitation employs a microplasma source in combination with a spectrometer. The microplasma source provides sufficient energy to produce excited acetone fragments from the breath gas that emit light. The emitted light is sent to the spectrometer, which generates an emission spectrum that is used to detect and quantify acetone in the breath gas.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 26 00:00:00 EDT 2008},
month = {Tue Aug 26 00:00:00 EDT 2008}
}
Works referenced in this record:
Variation in volatile organic compounds in the breath of normal humans
journal, June 1999
- Phillips, Michael; Herrera, Jolanta; Krishnan, Sunithi
- Journal of Chromatography B: Biomedical Sciences and Applications, Vol. 729, Issue 1-2
Breath-Acetone and Blood-Sugar Measurements in Diabetes
journal, June 1969
- Tassopoulos, C. N.; Barnett, D.; Russell Fraser, T.
- The Lancet, Vol. 293, Issue 7609
Acetone in Alveolar air, and the Control of Diabetes
journal, November 1966
- Rooth, Gösta; Östenson, Stig
- The Lancet, Vol. 288, Issue 7473
Simple, sensitive nitrogen analyzer based on pulsed miniplasma source emission spectrometry
journal, December 2003
- Jin, Zhe; Duan, Yixiang
- Review of Scientific Instruments, Vol. 74, Issue 12
Gas recognition using a neural network approach to plasma optical emission spectroscopy
conference, October 2000
- Hyland, Mark; Mariotti, Davide; Dubitzky, Werner
- International Symposium on Optical Science and Technology, SPIE Proceedings
Experimental study of breakdown voltage and effective secondary electron emission coefficient for a micro-plasma device
journal, February 2004
- Mariotti, D.; McLaughlin, J. A.; Maguire, P.
- Plasma Sources Science and Technology, Vol. 13, Issue 2
Measurements of Cavity Ringdown Spectroscopy of Acetone in the Ultraviolet and Near-Infrared Spectral Regions: Potential for Development of a Breath Analyzer
journal, July 2004
- Wang, Chuji; Scherrer, Susan T.; Hossain, Delwar
- Applied Spectroscopy, Vol. 58, Issue 7
Trace gases in breath of healthy volunteers when fasting and after a protein-calorie meal: a preliminary study
journal, November 1999
- Smith, David; Spanel, Patrik; Davies, Simon
- Journal of Applied Physiology, Vol. 87, Issue 5
A Low-Power, Atmospheric Pressure, Pulsed Plasma Source for Molecular Emission Spectrometry
journal, January 2001
- Jin, Zhe; Su, Yongxuan; Duan, Yixiang
- Analytical Chemistry, Vol. 73, Issue 2
GC Analysis of Human Breath with A Series-Coupled Column Ensemble and A Multibed Sorption Trap
journal, May 2003
- Sanchez, Juan M.; Sacks, Richard D.
- Analytical Chemistry, Vol. 75, Issue 10
Capillary-discharge-based portable detector for chemical vapor monitoring
journal, May 2003
- Duan, Yixiang; Su, Yongxuan; Jin, Zhe
- Review of Scientific Instruments, Vol. 74, Issue 5