Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure
Abstract
The invention discloses a new interface with non-circular conductance limit aperture(s) useful for effective transmission of non-circular ion beams between stages with different gas pressure. In particular, the invention provides an improved coupling of field asymmetric waveform ion mobility spectrometry (FAIMS) analyzers of planar or side-to-side geometry to downstream stages such as mass spectrometry or ion mobility spectrometry. In this case, the non-circular aperture is rectangular; other geometries may be optimum in other applications. In the preferred embodiment, the non-circular aperture interface is followed by an electrodynamic ion funnel that may focus wide ion beams of any shape into tight circular beams with virtually no losses. The jet disrupter element of the funnel may also have a non-circular geometry, matching the shape of arriving ion beam. The improved sensitivity of planar FAIMS/MS has been demonstrated in experiments using a non-contiguous elongated aperture but other embodiments (e.g., with a contiguous slit aperture) may be preferable, especially in conjunction with an ion funnel operated at high pressures.
- Inventors:
-
- Richland, WA
- Issue Date:
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 927858
- Patent Number(s):
- 7339166
- Application Number:
- 11/361,264
- Assignee:
- Battelle Memorial Institute (Richland, WA)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- AC05-76RL01830
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Tang, Keqi, Shvartsburg, Alexandre A, and Smith, Richard D. Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure. United States: N. p., 2008.
Web.
Tang, Keqi, Shvartsburg, Alexandre A, & Smith, Richard D. Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure. United States.
Tang, Keqi, Shvartsburg, Alexandre A, and Smith, Richard D. Tue .
"Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure". United States. https://www.osti.gov/servlets/purl/927858.
@article{osti_927858,
title = {Interface and process for enhanced transmission of non-circular ion beams between stages at unequal pressure},
author = {Tang, Keqi and Shvartsburg, Alexandre A and Smith, Richard D},
abstractNote = {The invention discloses a new interface with non-circular conductance limit aperture(s) useful for effective transmission of non-circular ion beams between stages with different gas pressure. In particular, the invention provides an improved coupling of field asymmetric waveform ion mobility spectrometry (FAIMS) analyzers of planar or side-to-side geometry to downstream stages such as mass spectrometry or ion mobility spectrometry. In this case, the non-circular aperture is rectangular; other geometries may be optimum in other applications. In the preferred embodiment, the non-circular aperture interface is followed by an electrodynamic ion funnel that may focus wide ion beams of any shape into tight circular beams with virtually no losses. The jet disrupter element of the funnel may also have a non-circular geometry, matching the shape of arriving ion beam. The improved sensitivity of planar FAIMS/MS has been demonstrated in experiments using a non-contiguous elongated aperture but other embodiments (e.g., with a contiguous slit aperture) may be preferable, especially in conjunction with an ion funnel operated at high pressures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 04 00:00:00 EST 2008},
month = {Tue Mar 04 00:00:00 EST 2008}
}
Works referenced in this record:
Comparison of the planar and coaxial field asymmetrical waveform ion mobility spectrometer (FAIMS)
journal, February 2003
- Krylov, E. V.
- International Journal of Mass Spectrometry, Vol. 225, Issue 1
Optimization of the design and operation of FAIMS analyzers
journal, January 2005
- Shvartsburg, Alexandre A.; Tang, Keqi; Smith, Richard D.
- Journal of the American Society for Mass Spectrometry, Vol. 16, Issue 1
High-Sensitivity Ion Mobility Spectrometry/Mass Spectrometry Using Electrodynamic Ion Funnel Interfaces
journal, May 2005
- Tang, Keqi; Shvartsburg, Alexandre A.; Lee, Hak-No
- Analytical Chemistry, Vol. 77, Issue 10, p. 3330-3339