Methods for assisting recovery of damaged brain and spinal cord using arrays of X-Ray microplanar beams
Abstract
A method of assisting recovery of an injury site of brain or spinal cord injury includes providing a therapeutic dose of X-ray radiation to the injury site through an array of parallel microplanar beams. The dose at least temporarily removes regeneration inhibitors from the irradiated regions. Substantially unirradiated cells surviving between the microplanar beams migrate to the in-beam irradiated portion and assist in recovery. The dose may be administered in dose fractions over several sessions, separated in time, using angle-variable intersecting microbeam arrays (AVIMA). Additional doses may be administered by varying the orientation of the microplanar beams. The method may be enhanced by injecting stem cells into the injury site.
- Inventors:
-
- Yaphank, NY
- (Baltimore, MD)
- Issue Date:
- Research Org.:
- Brookhaven National Laboratory (BNL), Upton, NY (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 920653
- Patent Number(s):
- 7305064
- Application Number:
- 11/591,125
- Assignee:
- Brookhaven Science Associates, LLC (Upton, NY)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61N - ELECTROTHERAPY
- DOE Contract Number:
- AC02-98CH10886
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Dilmanian, F Avraham, and McDonald, III, John W. Methods for assisting recovery of damaged brain and spinal cord using arrays of X-Ray microplanar beams. United States: N. p., 2007.
Web.
Dilmanian, F Avraham, & McDonald, III, John W. Methods for assisting recovery of damaged brain and spinal cord using arrays of X-Ray microplanar beams. United States.
Dilmanian, F Avraham, and McDonald, III, John W. Tue .
"Methods for assisting recovery of damaged brain and spinal cord using arrays of X-Ray microplanar beams". United States. https://www.osti.gov/servlets/purl/920653.
@article{osti_920653,
title = {Methods for assisting recovery of damaged brain and spinal cord using arrays of X-Ray microplanar beams},
author = {Dilmanian, F Avraham and McDonald, III, John W.},
abstractNote = {A method of assisting recovery of an injury site of brain or spinal cord injury includes providing a therapeutic dose of X-ray radiation to the injury site through an array of parallel microplanar beams. The dose at least temporarily removes regeneration inhibitors from the irradiated regions. Substantially unirradiated cells surviving between the microplanar beams migrate to the in-beam irradiated portion and assist in recovery. The dose may be administered in dose fractions over several sessions, separated in time, using angle-variable intersecting microbeam arrays (AVIMA). Additional doses may be administered by varying the orientation of the microplanar beams. The method may be enhanced by injecting stem cells into the injury site.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 04 00:00:00 EST 2007},
month = {Tue Dec 04 00:00:00 EST 2007}
}