Tissue-like phantoms
Abstract
The invention is based, in part, on the discovery that by combining certain components one can generate a tissue-like phantom that mimics any desired tissue, is simple and inexpensive to prepare, and is stable over many weeks or months. In addition, new multi-modal imaging objects (e.g., beads) can be inserted into the phantoms to mimic tissue pathologies, such as cancer, or merely to serve as calibration standards. These objects can be imaged using one, two, or more (e.g., four) different imaging modalities (e.g., x-ray computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and near-infrared (NIR) fluorescence) simultaneously.
- Inventors:
-
- Wayland, MA
- Boston, MA
- Issue Date:
- Research Org.:
- Beth Israel Deaconess Medical Center, Inc. (Boston, MA)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 918907
- Patent Number(s):
- 7288759
- Application Number:
- 11/222,949
- Assignee:
- Beth Israel Deaconess Medical Center, Inc. (Boston, MA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG02-01ER63188
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Frangioni, John V, and De Grand, Alec M. Tissue-like phantoms. United States: N. p., 2007.
Web.
Frangioni, John V, & De Grand, Alec M. Tissue-like phantoms. United States.
Frangioni, John V, and De Grand, Alec M. Tue .
"Tissue-like phantoms". United States. https://www.osti.gov/servlets/purl/918907.
@article{osti_918907,
title = {Tissue-like phantoms},
author = {Frangioni, John V and De Grand, Alec M},
abstractNote = {The invention is based, in part, on the discovery that by combining certain components one can generate a tissue-like phantom that mimics any desired tissue, is simple and inexpensive to prepare, and is stable over many weeks or months. In addition, new multi-modal imaging objects (e.g., beads) can be inserted into the phantoms to mimic tissue pathologies, such as cancer, or merely to serve as calibration standards. These objects can be imaged using one, two, or more (e.g., four) different imaging modalities (e.g., x-ray computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and near-infrared (NIR) fluorescence) simultaneously.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 30 00:00:00 EDT 2007},
month = {Tue Oct 30 00:00:00 EDT 2007}
}
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Works referenced in this record:
Validation of a near-infrared probe for detection of thin intracranial white matter structures
journal, June 2003
- Giller, Cole A.; Liu, Hanli; Gurnani, Prem
- Journal of Neurosurgery, Vol. 98, Issue 6
Determination of complex refractive index of polystyrene microspheres from 370 to 1610 nm
journal, December 2003
- Ma, Xiaoyan; Lu, Jun Q.; Brock, R. Scott
- Physics in Medicine and Biology, Vol. 48, Issue 24
In vivo near-infrared fluorescence imaging
journal, October 2003
- Frangioni, J.
- Current Opinion in Chemical Biology, Vol. 7, Issue 5, p. 626-634
Contrast-Enhanced Near-Infrared Laser Mammography with a Prototype Breast Scanner: Feasibility Study with Tissue Phantoms and Preliminary Results of Imaging Experimental Tumors
journal, January 2001
- Boehm, Thomas; Hochmuth, Albrecht; Malich, Ansgar
- Investigative Radiology, Vol. 36, Issue 10
Optical CT reconstruction of 3D dose distributions using the ferrous-benzoic-xylenol (FBX) gel dosimeter
journal, September 1998
- Kelly, R. G.; Jordan, K. J.; Battista, J. J.
- Medical Physics, Vol. 25, Issue 9
In vivo near-infrared fluorescence imaging of osteoblastic activity
journal, December 2001
- Zaheer, Atif; Lenkinski, Robert E.; Mahmood, Ashfaq
- Nature Biotechnology, Vol. 19, Issue 12
An Operational Near-Infrared Fluorescence Imaging System Prototype for Large Animal Surgery
journal, December 2003
- De Grand, Alec M.; Frangioni, John V.
- Technology in Cancer Research & Treatment, Vol. 2, Issue 6
Sub-Millimeter Technetium-99m Calibration Sources
journal, October 2002
- English, J.
- Molecular Imaging & Biology, Vol. 4, Issue 5
A review of the optical properties of biological tissues
journal, January 1990
- Cheong, W. F.; Prahl, S. A.; Welch, A. J.
- IEEE Journal of Quantum Electronics, Vol. 26, Issue 12
Tissue-like phantoms for near-infrared fluorescence imaging system assessment and the training of surgeons
journal, January 2006
- De Grand, Alec M.; Lomnes, Stephen J.; Lee, Deborah S.
- Journal of Biomedical Optics, Vol. 11, Issue 1
Quantitative analysis of near-infrared tomography: sensitivity to the tissue-simulating precalibration phantom
journal, January 2003
- Jiang, Shudong; Pogue, Brian W.; McBride, Troy O.
- Journal of Biomedical Optics, Vol. 8, Issue 2
A solid tissue phantom for photon migration studies
journal, October 1997
- Cubeddu, Rinaldo; Pifferi, Antonio; Taroni, Paola
- Physics in Medicine and Biology, Vol. 42, Issue 10
Determining the optical properties of turbid media by using the adding–doubling method
journal, January 1993
- Prahl, Scott A.; van Gemert, Martin J. C.; Welch, Ashley J.
- Applied Optics, Vol. 32, Issue 4
Glucose determination by a pulsed photoacoustic technique: an experimental study using a gelatin-based tissue phantom
journal, December 1993
- Quan, K. M.; Christison, G. B.; MacKenzie, H. A.
- Physics in Medicine and Biology, Vol. 38, Issue 12
An optical phantom with tissue-like properties in the visible for use in PDT and fluorescence spectroscopy
journal, July 1997
- Wagnières, Georges; Cheng, Shangguan; Zellweger, Matthieu
- Physics in Medicine and Biology, Vol. 42, Issue 7