Oncoprotein protein kinase
Abstract
The present invention provides an isolated polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set fort in SEQ ID NO: 10 or conservative variations thereof. The invention also provides a method for producing a peptide of SEQ ID NO:1 comprising (a) culturing a host cell containing a polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set forth in SEQ ID NO: 10 under conditions which allow expression of the polynucleotide; and (b) obtaining the peptide of SEQ ID NO:1.
- Inventors:
-
- San Diego, CA
- La Jolla, CA
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- OSTI Identifier:
- 874218
- Patent Number(s):
- 6342595
- Application Number:
- 09/461649
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- FG03-86ER60429
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- oncoprotein; protein; kinase; provides; isolated; polynucleotide; encoding; c-jun; peptide; consisting; amino; acid; residues; 33; 79; set; fort; seq; 10; conservative; variations; method; producing; no1; comprising; culturing; host; cell; containing; forth; conditions; allow; expression; obtaining; amino acid; set forth; protein kinase; oncoprotein protein; acid residue; /999/435/
Citation Formats
Karin, Michael, Hibi, Masahiko, and Lin, Anning. Oncoprotein protein kinase. United States: N. p., 2002.
Web.
Karin, Michael, Hibi, Masahiko, & Lin, Anning. Oncoprotein protein kinase. United States.
Karin, Michael, Hibi, Masahiko, and Lin, Anning. Tue .
"Oncoprotein protein kinase". United States. https://www.osti.gov/servlets/purl/874218.
@article{osti_874218,
title = {Oncoprotein protein kinase},
author = {Karin, Michael and Hibi, Masahiko and Lin, Anning},
abstractNote = {The present invention provides an isolated polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set fort in SEQ ID NO: 10 or conservative variations thereof. The invention also provides a method for producing a peptide of SEQ ID NO:1 comprising (a) culturing a host cell containing a polynucleotide encoding a c-Jun peptide consisting of about amino acid residues 33 to 79 as set forth in SEQ ID NO: 10 under conditions which allow expression of the polynucleotide; and (b) obtaining the peptide of SEQ ID NO:1.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 01 00:00:00 EST 2002},
month = {Tue Jan 01 00:00:00 EST 2002}
}
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Works referenced in this record:
c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases.
journal, October 1994
- Minden, A.; Lin, A.; Smeal, T.
- Molecular and Cellular Biology, Vol. 14, Issue 10
pp54 microtubule-associated protein 2 kinase. A novel serine/threonine protein kinase regulated by phosphorylation and stimulated by poly-L-lysine.
journal, October 1990
- Kyriakis, J. M.; Avruch, J.
- Journal of Biological Chemistry, Vol. 265, Issue 28
An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control
journal, July 1990
- Boulton, T.; Yancopoulos, G.; Gregory, J.
- Science, Vol. 249, Issue 4964
Requirement for integration of signals from two distinct phosphorylation pathways for activation of MAP kinase
journal, February 1990
- Anderson, Neil G.; Maller, James L.; Tonks, Nicholas K.
- Nature, Vol. 343, Issue 6259
Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.
journal, November 1993
- Hibi, M.; Lin, A.; Smeal, T.
- Genes & Development, Vol. 7, Issue 11
Phorbol esters stimulate the phosphorylation of c-Jun but not v-Jun: regulation by the N-terminal delta domain.
journal, June 1992
- Adler, V.; Franklin, C. C.; Kraft, A. S.
- Proceedings of the National Academy of Sciences, Vol. 89, Issue 12
ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF
journal, May 1991
- Boulton, Teri G.; Nye, Steven H.; Robbins, David J.
- Cell, Vol. 65, Issue 4
Parallel signal processing among mammalian MAPKs
journal, March 1995
- Cano, Eva; Mahadevan, Louis C.
- Trends in Biochemical Sciences, Vol. 20, Issue 3
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
journal, March 1994
- Dérijard, Benoit; Hibi, Masahiko; Wu, I-Huan
- Cell, Vol. 76, Issue 6
Phosphorylation of c-jun mediated by MAP kinases
journal, October 1991
- Pulverer, Bernd J.; Kyriakis, John M.; Avruch, Joseph
- Nature, Vol. 353, Issue 6345