Agouti polypeptide compositions
Abstract
Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.
- Inventors:
-
- Orinda, CA
- Lakewood, OH
- Kingston, TN
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- OSTI Identifier:
- 874092
- Patent Number(s):
- 6310034
- Application Number:
- 09/034,088
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A01 - AGRICULTURE A01K - ANIMAL HUSBANDRY
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- agouti; polypeptide; compositions; disclosed; methods; comprising; novel; polypeptides; polynucleotides; encode; dna; segments; encoding; proteins; derived; human; murine; cell; lines; variety; diagnostic; therapeutic; applications; kits; devices; provided; identifying; compounds; inhibitors; activity; altering; fatty; acid; synthetase; intracellular; calcium; levels; transformed; cells; fatty acid; cell line; /514/530/
Citation Formats
Woychik, Richard P, Bultman, Scott J, and Michaud, Edward J. Agouti polypeptide compositions. United States: N. p., 2001.
Web.
Woychik, Richard P, Bultman, Scott J, & Michaud, Edward J. Agouti polypeptide compositions. United States.
Woychik, Richard P, Bultman, Scott J, and Michaud, Edward J. Tue .
"Agouti polypeptide compositions". United States. https://www.osti.gov/servlets/purl/874092.
@article{osti_874092,
title = {Agouti polypeptide compositions},
author = {Woychik, Richard P and Bultman, Scott J and Michaud, Edward J},
abstractNote = {Disclosed are methods and compositions comprising novel agouti polypeptides and the polynucleotides which encode them. Also disclosed are DNA segments encoding these proteins derived from human and murine cell lines, and the use of these polynucleotides and polypeptides in a variety of diagnostic and therapeutic applications. Methods, compositions, kits, and devices are also provided for identifying compounds which are inhibitors of agouti activity, and for altering fatty acid synthetase activity and intracellular calcium levels in transformed cells.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 30 00:00:00 EST 2001},
month = {Tue Oct 30 00:00:00 EST 2001}
}
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