Title: Microorganism genomics, compositions and methods related thereto

Abstract

The present invention provides methods and compositions for accessing, in a generally unbaised manner, a diverse genetic pool for genes involved in biosynthetic pathways. The invention also provides compounds which can be identified by cloning biosynthetic pathways.

Inventors:

Handelsman, Jo ^[1]; Goodman, Robert M ^[1]; Rondon, Michelle R ^[1]

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1. Madison, WI

Issue Date:

Mon Jan 01 00:00:00 EST 2001

Research Org.:

Univ. of Wisconsin, Madison, WI (United States)

OSTI Identifier:

873859

Patent Number(s):

6261842

Assignee:

Wisconsin Alumni Research Foundation (Madison, WI)

Patent Classifications (CPCs):

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

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C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N15/1034 - {Isolating an individual clone by screening libraries}
C12N15/1079 - {Screening libraries by altering the phenotype or phenotypic trait of the host
C12N15/1093 - {General methods of preparing gene libraries, not provided for in other subgroups}
C12N15/52 - Genes encoding for enzymes or proenzymes
C12N15/75 - for Bacillus

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

C12Q1/6897 - involving reporter genes operably linked to promoters

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DOE Contract Number:  

FG02-96ER20248

Resource Type:

Patent

Country of Publication:

United States

Language:

English

Subject:

microorganism; genomics; compositions; methods; related; provides; accessing; unbaised; manner; diverse; genetic; pool; genes; involved; biosynthetic; pathways; compounds; identified; cloning; provides methods; methods related; /435/999/