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Title: Piezoelectric biosensor with a ladder polymer substrate coating

Abstract

A piezoelectric biosensor substrate useful for immobilizing biomolecules in an oriented manner on the surface of a piezoelectric sensor has a ladder polymer of polyacrylonitrile. To make the substrate, a solution of an organic polymer, preferably polyacrylonitrile, is applied to the surface of a piezoelectric sensor. The organic polymer is modifying by heating the polymer in a controlled fashion in air such that a ladder polymer is produced which, in turn, forms the attachment point for the biomolecules comprising the piezoelectric biosensor.

Inventors:
 [1];  [2];  [3]
  1. Tijeras, NM
  2. Albuquerque, NM
  3. New Orleans, LA
Issue Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
OSTI Identifier:
871870
Patent Number(s):
5814525
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
piezoelectric; biosensor; ladder; polymer; substrate; coating; useful; immobilizing; biomolecules; oriented; manner; surface; sensor; polyacrylonitrile; solution; organic; preferably; applied; modifying; heating; controlled; fashion; air; produced; forms; attachment; comprising; piezoelectric sensor; organic polymer; piezoelectric biosensor; polymer substrate; molecules comprising; sensor substrate; ladder polymer; immobilizing biomolecules; controlled fashion; /436/310/422/427/435/

Citation Formats

Renschler, Clifford L, White, Christine A, and Carter, Robert M. Piezoelectric biosensor with a ladder polymer substrate coating. United States: N. p., 1998. Web.
Renschler, Clifford L, White, Christine A, & Carter, Robert M. Piezoelectric biosensor with a ladder polymer substrate coating. United States.
Renschler, Clifford L, White, Christine A, and Carter, Robert M. Thu . "Piezoelectric biosensor with a ladder polymer substrate coating". United States. https://www.osti.gov/servlets/purl/871870.
@article{osti_871870,
title = {Piezoelectric biosensor with a ladder polymer substrate coating},
author = {Renschler, Clifford L and White, Christine A and Carter, Robert M},
abstractNote = {A piezoelectric biosensor substrate useful for immobilizing biomolecules in an oriented manner on the surface of a piezoelectric sensor has a ladder polymer of polyacrylonitrile. To make the substrate, a solution of an organic polymer, preferably polyacrylonitrile, is applied to the surface of a piezoelectric sensor. The organic polymer is modifying by heating the polymer in a controlled fashion in air such that a ladder polymer is produced which, in turn, forms the attachment point for the biomolecules comprising the piezoelectric biosensor.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 1998},
month = {Thu Jan 01 00:00:00 EST 1998}
}