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Title: Method for replicating an array of nucleic acid probes

Abstract

The invention relates to the replication of probe arrays and methods for replicating arrays of probes which are useful for the large scale manufacture of diagnostic aids used to screen biological samples for specific target sequences. Arrays created using PCR technology may comprise probes with 5'- and/or 3'-overhangs.

Inventors:
 [1];  [1];  [1];  [1]
  1. Boston, MA
Issue Date:
OSTI Identifier:
871784
Patent Number(s):
5795714
Assignee:
Trustees of Boston University (Boston, MA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
PO4591610
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; replicating; array; nucleic; acid; probes; relates; replication; probe; arrays; methods; useful; scale; manufacture; diagnostic; aids; screen; biological; samples; specific; target; sequences; created; pcr; technology; comprise; -overhangs; biological samples; acid probes; nucleic acid; target sequence; acid probe; specific target; biological sample; /435/999/

Citation Formats

Cantor, Charles R, Przetakiewicz, Marek, Smith, Cassandra L, and Sano, Takeshi. Method for replicating an array of nucleic acid probes. United States: N. p., 1998. Web.
Cantor, Charles R, Przetakiewicz, Marek, Smith, Cassandra L, & Sano, Takeshi. Method for replicating an array of nucleic acid probes. United States.
Cantor, Charles R, Przetakiewicz, Marek, Smith, Cassandra L, and Sano, Takeshi. Thu . "Method for replicating an array of nucleic acid probes". United States. https://www.osti.gov/servlets/purl/871784.
@article{osti_871784,
title = {Method for replicating an array of nucleic acid probes},
author = {Cantor, Charles R and Przetakiewicz, Marek and Smith, Cassandra L and Sano, Takeshi},
abstractNote = {The invention relates to the replication of probe arrays and methods for replicating arrays of probes which are useful for the large scale manufacture of diagnostic aids used to screen biological samples for specific target sequences. Arrays created using PCR technology may comprise probes with 5'- and/or 3'-overhangs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 01 00:00:00 EST 1998},
month = {Thu Jan 01 00:00:00 EST 1998}
}

Works referenced in this record:

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Optical properties of specific complexes between complementary oligoribonucleotides
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Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide
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Reliable Hybridization of Oligonucleotides as Short as Six Nucleotides
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Analytical strategies for the use of DNA probes
journal, February 1988


1-Tuple DNA Sequencing: Computer Analysis
journal, August 1989


DNA sequencing by hybridization: 100 bases read by a non-gel-based method.
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Encoded combinatorial chemistry.
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