Technetium-99m generator system
Abstract
A .sup.99 Mo/.sup.99m Tc generator system includes a sorbent column loaded with a composition containing .sup.99 Mo. The sorbent column has an effluent end in fluid communication with an anion-exchange column for concentrating .sup.99m Tc eluted from the sorbent column. A method of preparing a concentrated solution of .sup.99m Tc includes the general steps of: a. providing a sorbent column loaded with a composition containing .sup.99 Mo, the sorbent column having an effluent end in fluid communication with an anion-exchange column; b. eluting the sorbent column with a salt solution to elute .sup.99m Tc from the sorbent and to trap and concentrate the eluted .sup.99m Tc on the ion-exchange column; and c. eluting the concentrated .sup.99m Tc from the ion-exchange column with a solution comprising a reductive complexing agent.
- Inventors:
-
- Knoxville, TN
- (Oak Ridge, TN)
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- OSTI Identifier:
- 871674
- Patent Number(s):
- 5774782
- Assignee:
- Lockheed Martin Energy Systems, Inc. (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
G - PHYSICS G21 - NUCLEAR PHYSICS G21G - CONVERSION OF CHEMICAL ELEMENTS
- DOE Contract Number:
- AC05-84OR21400
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- technetium-99m; generator; 99; 99m; tc; sorbent; column; loaded; composition; containing; effluent; fluid; communication; anion-exchange; concentrating; eluted; method; preparing; concentrated; solution; steps; providing; eluting; salt; elute; trap; concentrate; ion-exchange; comprising; reductive; complexing; agent; sorbent column; concentrated solution; exchange column; salt solution; fluid communication; solution comprising; composition containing; complexing agent; ion-exchange column; column loaded; anion-exchange column; /423/210/250/424/
Citation Formats
Mirzadeh, Saed, Knapp, Jr., Furn F., and Collins, Emory D. Technetium-99m generator system. United States: N. p., 1998.
Web.
Mirzadeh, Saed, Knapp, Jr., Furn F., & Collins, Emory D. Technetium-99m generator system. United States.
Mirzadeh, Saed, Knapp, Jr., Furn F., and Collins, Emory D. Tue .
"Technetium-99m generator system". United States. https://www.osti.gov/servlets/purl/871674.
@article{osti_871674,
title = {Technetium-99m generator system},
author = {Mirzadeh, Saed and Knapp, Jr., Furn F. and Collins, Emory D},
abstractNote = {A .sup.99 Mo/.sup.99m Tc generator system includes a sorbent column loaded with a composition containing .sup.99 Mo. The sorbent column has an effluent end in fluid communication with an anion-exchange column for concentrating .sup.99m Tc eluted from the sorbent column. A method of preparing a concentrated solution of .sup.99m Tc includes the general steps of: a. providing a sorbent column loaded with a composition containing .sup.99 Mo, the sorbent column having an effluent end in fluid communication with an anion-exchange column; b. eluting the sorbent column with a salt solution to elute .sup.99m Tc from the sorbent and to trap and concentrate the eluted .sup.99m Tc on the ion-exchange column; and c. eluting the concentrated .sup.99m Tc from the ion-exchange column with a solution comprising a reductive complexing agent.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 30 00:00:00 EDT 1998},
month = {Tue Jun 30 00:00:00 EDT 1998}
}
Works referenced in this record:
Highly concentrated [99mTc]pertechnetate solutions from (n,γ)99Mo/99mTc generators for nuclear medical use
journal, May 1994
- Seifert, Sepp; Wagner, Gerhard; Eckardt, Armin
- Applied Radiation and Isotopes, Vol. 45, Issue 5