Nuclear magnetic resonance contrast agents
Abstract
A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.
- Inventors:
-
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- OSTI Identifier:
- 871291
- Patent Number(s):
- 5702683
- Assignee:
- United States of America as represented by United States (Washington, DC)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- nuclear; magnetic; resonance; contrast; agents; family; imaging; method; enhancing; images; incorporating; agent; prior; forming; formation; paramagnetic; lanthanide; hexaazamacrocyclic; molecule; basic; example; formula; lnc; 16; 14; applications; medical; diagnosis; treatment; portions; human; formed; means; techniques; resonance imaging; magnetic resonance; nuclear magnetic; resonance techniques; medical diagnosis; contrast agents; contrast agent; /424/436/999/
Citation Formats
Smith, Paul H, Brainard, James R, Jarvinen, Gordon D, and Ryan, Robert R. Nuclear magnetic resonance contrast agents. United States: N. p., 1997.
Web.
Smith, Paul H, Brainard, James R, Jarvinen, Gordon D, & Ryan, Robert R. Nuclear magnetic resonance contrast agents. United States.
Smith, Paul H, Brainard, James R, Jarvinen, Gordon D, and Ryan, Robert R. Wed .
"Nuclear magnetic resonance contrast agents". United States. https://www.osti.gov/servlets/purl/871291.
@article{osti_871291,
title = {Nuclear magnetic resonance contrast agents},
author = {Smith, Paul H and Brainard, James R and Jarvinen, Gordon D and Ryan, Robert R},
abstractNote = {A family of contrast agents for use in magnetic resonance imaging and a method of enhancing the contrast of magnetic resonance images of an object by incorporating a contrast agent of this invention into the object prior to forming the images or during formation of the images. A contrast agent of this invention is a paramagnetic lanthanide hexaazamacrocyclic molecule, where a basic example has the formula LnC.sub.16 H.sub.14 N.sub.6. Important applications of the invention are in medical diagnosis, treatment, and research, where images of portions of a human body are formed by means of magnetic resonance techniques.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1997},
month = {Wed Jan 01 00:00:00 EST 1997}
}
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