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Title: Method and apparatus for imaging a sample on a device

Abstract

The present invention provides methods and systems for detecting a labeled marker on a sample located on a support. The imaging system comprises a body for immobilizing the support, an excitation radiation source and excitation optics to generate and direct the excitation radiation at the sample. In response, labeled material on the sample emits radiation which has a wavelength that is different from the excitation wavelength, which radiation is collected by collection optics and imaged onto a detector which generates an image of the sample.

Inventors:
 [1];  [2];  [3];  [4];  [5];  [4]
+ Show Inventor Affiliations
  1. Santa Clara, CA
  2. Mountain View, CA
  3. Los Altos, CA
  4. Palo Alto, CA
  5. Menlo Park, CA
Issue Date:
Research Org.:
Affymax Research Institute
OSTI Identifier:
870702
Patent Number(s):
5578832
Assignee:
Affymetrix, Inc. (Santa Clara, CA)
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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DOE Contract Number:  
FG03-92ER81275
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; apparatus; imaging; sample; device; provides; methods; systems; detecting; labeled; marker; located; support; comprises; immobilizing; excitation; radiation; source; optics; generate; direct; response; material; emits; wavelength; collected; collection; imaged; detector; generates; image; excitation radiation; provides methods; radiation source; collection optics; sample located; excitation optics; /250/

Citation Formats

Trulson, Mark, Stern, David, Fiekowsky, Peter, Rava, Richard, Walton, Ian, and Fodor, Stephen P. A. Method and apparatus for imaging a sample on a device. United States: N. p., 1996. Web.
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Trulson, Mark, Stern, David, Fiekowsky, Peter, Rava, Richard, Walton, Ian, & Fodor, Stephen P. A. Method and apparatus for imaging a sample on a device. United States.
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Trulson, Mark, Stern, David, Fiekowsky, Peter, Rava, Richard, Walton, Ian, and Fodor, Stephen P. A. Mon . "Method and apparatus for imaging a sample on a device". United States. https://www.osti.gov/servlets/purl/870702.
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@article{osti_870702,
title = {Method and apparatus for imaging a sample on a device},
author = {Trulson, Mark and Stern, David and Fiekowsky, Peter and Rava, Richard and Walton, Ian and Fodor, Stephen P. A.},
abstractNote = {The present invention provides methods and systems for detecting a labeled marker on a sample located on a support. The imaging system comprises a body for immobilizing the support, an excitation radiation source and excitation optics to generate and direct the excitation radiation at the sample. In response, labeled material on the sample emits radiation which has a wavelength that is different from the excitation wavelength, which radiation is collected by collection optics and imaged onto a detector which generates an image of the sample.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 1996},
month = {Mon Jan 01 00:00:00 EST 1996}
}
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