Rotor assembly and method for automatically processing liquids
Abstract
A rotor assembly for performing a relatively large number of processing steps upon a sample, such as a whole blood sample, and a diluent, such as water, includes a rotor body for rotation about an axis and including a network of chambers within which various processing steps are performed upon the sample and diluent and passageways through which the sample and diluent are transferred. A transfer mechanism is movable through the rotor body by the influence of a magnetic field generated adjacent the transfer mechanism and movable along the rotor body, and the assembly utilizes centrifugal force, a transfer of momentum and capillary action to perform any of a number of processing steps such as separation, aliquoting, transference, washing, reagent addition and mixing of the sample and diluent within the rotor body. The rotor body is particularly suitable for automatic immunoassay analyses.
- Inventors:
-
- Oak Ridge, TN
- Loudon, TN
- Knoxville, TN
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- OSTI Identifier:
- 868602
- Patent Number(s):
- 5173262
- Assignee:
- Martin Marietta Energy Systems, Inc. (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B - PERFORMING OPERATIONS B04 - CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES B04B - CENTRIFUGES
- DOE Contract Number:
- AC05-84OR21400
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- rotor; assembly; method; automatically; processing; liquids; performing; relatively; steps; sample; blood; diluent; water; rotation; axis; including; network; chambers; various; performed; passageways; transferred; transfer; mechanism; movable; influence; magnetic; field; generated; adjacent; utilizes; centrifugal; force; momentum; capillary; action; perform; separation; aliquoting; transference; washing; reagent; addition; mixing; particularly; suitable; automatic; immunoassay; analyses; blood sample; centrifugal force; rotor assembly; particularly suitable; magnetic field; processing steps; field generated; capillary action; assembly utilizes; processing step; processing liquids; transfer mechanism; /422/436/494/
Citation Formats
Burtis, Carl A, Johnson, Wayne F, and Walker, William A. Rotor assembly and method for automatically processing liquids. United States: N. p., 1992.
Web.
Burtis, Carl A, Johnson, Wayne F, & Walker, William A. Rotor assembly and method for automatically processing liquids. United States.
Burtis, Carl A, Johnson, Wayne F, and Walker, William A. Wed .
"Rotor assembly and method for automatically processing liquids". United States. https://www.osti.gov/servlets/purl/868602.
@article{osti_868602,
title = {Rotor assembly and method for automatically processing liquids},
author = {Burtis, Carl A and Johnson, Wayne F and Walker, William A},
abstractNote = {A rotor assembly for performing a relatively large number of processing steps upon a sample, such as a whole blood sample, and a diluent, such as water, includes a rotor body for rotation about an axis and including a network of chambers within which various processing steps are performed upon the sample and diluent and passageways through which the sample and diluent are transferred. A transfer mechanism is movable through the rotor body by the influence of a magnetic field generated adjacent the transfer mechanism and movable along the rotor body, and the assembly utilizes centrifugal force, a transfer of momentum and capillary action to perform any of a number of processing steps such as separation, aliquoting, transference, washing, reagent addition and mixing of the sample and diluent within the rotor body. The rotor body is particularly suitable for automatic immunoassay analyses.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1992},
month = {Wed Jan 01 00:00:00 EST 1992}
}
Works referenced in this record:
Two-dimensional centrifugation for desk-top clinical chemistry.
journal, September 1985
- Schultz, S. G.; Holen, J. T.; Donohue, J. P.
- Clinical Chemistry, Vol. 31, Issue 9
Development of a simple device for processing whole-blood samples into measured aliquots of plasma.
journal, September 1986
- Burtis, C. A.; Johnson, W. F.; Walker, W. A.
- Clinical Chemistry, Vol. 32, Issue 9