Cyanobacteriochromes active in the far-red to near-infrared
Abstract
The present invention provides a protein fusion construct comprising a far-red cyanobacteriochrome (CBCR) domain linked to a heterologous domain, wherein the far-red CBCR domain comprises a CBCR polypeptide and a tetrapyrrole chromophore. The invention also provides nucleic acids, expression cassettes, vectors, and host cells for expression of the far-red CBCR protein fusion constructs. Methods for detecting cellular components, methods for imaging biological structures, and method for modulating cellular processes using the protein fusion constructs are also provided.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Davis, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1824015
- Patent Number(s):
- 11021523
- Application Number:
- 16/109,613
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- SC0002395
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 08/22/2018
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Lagarias, John Clark, and Rockwell, Nathan Clarke. Cyanobacteriochromes active in the far-red to near-infrared. United States: N. p., 2021.
Web.
Lagarias, John Clark, & Rockwell, Nathan Clarke. Cyanobacteriochromes active in the far-red to near-infrared. United States.
Lagarias, John Clark, and Rockwell, Nathan Clarke. Tue .
"Cyanobacteriochromes active in the far-red to near-infrared". United States. https://www.osti.gov/servlets/purl/1824015.
@article{osti_1824015,
title = {Cyanobacteriochromes active in the far-red to near-infrared},
author = {Lagarias, John Clark and Rockwell, Nathan Clarke},
abstractNote = {The present invention provides a protein fusion construct comprising a far-red cyanobacteriochrome (CBCR) domain linked to a heterologous domain, wherein the far-red CBCR domain comprises a CBCR polypeptide and a tetrapyrrole chromophore. The invention also provides nucleic acids, expression cassettes, vectors, and host cells for expression of the far-red CBCR protein fusion constructs. Methods for detecting cellular components, methods for imaging biological structures, and method for modulating cellular processes using the protein fusion constructs are also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 01 00:00:00 EDT 2021},
month = {Tue Jun 01 00:00:00 EDT 2021}
}
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Works referenced in this record:
Cyanochrome Fluorophores
patent-application, February 2015
- Ulijasz, Andrew T.; Vierstra, Richard D.
- US Patent Application 14/464751; 20150056646