Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway
Abstract
The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.
- Inventors:
- Issue Date:
- Research Org.:
- Gingko Bioworks, Inc., Boston, MA (United States)
- Sponsoring Org.:
- USDOE Advanced Research Projects Agency - Energy (ARPA-E)
- OSTI Identifier:
- 1771496
- Patent Number(s):
- 10801045
- Application Number:
- 15/867,209
- Assignee:
- Ginkgo Bioworks, Inc. (Boston, MA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- AR0000091
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 01/10/2018
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Fischer, Curt R., Che, Austin J., Shetty, Reshma P., and Kelly, Jason R. Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway. United States: N. p., 2020.
Web.
Fischer, Curt R., Che, Austin J., Shetty, Reshma P., & Kelly, Jason R. Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway. United States.
Fischer, Curt R., Che, Austin J., Shetty, Reshma P., and Kelly, Jason R. Tue .
"Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway". United States. https://www.osti.gov/servlets/purl/1771496.
@article{osti_1771496,
title = {Methods for making chemoautotrophic cells by engineering an energy conversion pathway and a carbon fixation pathway},
author = {Fischer, Curt R. and Che, Austin J. and Shetty, Reshma P. and Kelly, Jason R.},
abstractNote = {The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 13 00:00:00 EDT 2020},
month = {Tue Oct 13 00:00:00 EDT 2020}
}
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