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Title: Methods for treating diseases related to the wnt pathway

Abstract

The present invention relates to methods for treating a disease, in which the disease arises from dysregulation of the Wnt signaling pathway. In some instances, the disease can be treated by administering a Wnt pathway inhibitory compound. In other instances, the method optionally includes conducting a genome-wide screening to determine one or more genes resulting in a reduced disease state and then identifying the gene(s) as being involved in the Wnt signaling pathway.

Inventors:
;
Issue Date:
Research Org.:
Sandia National Lab. (SNL-CA), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1650782
Patent Number(s):
10624949
Application Number:
15/204,804
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Resource Relation:
Patent File Date: 07/07/2016
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Negrete, Oscar A., and Harmon, Brooke Nicole. Methods for treating diseases related to the wnt pathway. United States: N. p., 2020. Web.
Negrete, Oscar A., & Harmon, Brooke Nicole. Methods for treating diseases related to the wnt pathway. United States.
Negrete, Oscar A., and Harmon, Brooke Nicole. Tue . "Methods for treating diseases related to the wnt pathway". United States. https://www.osti.gov/servlets/purl/1650782.
@article{osti_1650782,
title = {Methods for treating diseases related to the wnt pathway},
author = {Negrete, Oscar A. and Harmon, Brooke Nicole},
abstractNote = {The present invention relates to methods for treating a disease, in which the disease arises from dysregulation of the Wnt signaling pathway. In some instances, the disease can be treated by administering a Wnt pathway inhibitory compound. In other instances, the method optionally includes conducting a genome-wide screening to determine one or more genes resulting in a reduced disease state and then identifying the gene(s) as being involved in the Wnt signaling pathway.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 21 00:00:00 EDT 2020},
month = {Tue Apr 21 00:00:00 EDT 2020}
}

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