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Title: NNA-DNA adducts as biomarkers for detecting exposure to thirdhand smoke

Abstract

NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1632461
Patent Number(s):
10538549
Application Number:
14/659,588
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07H - SUGARS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 03/16/2015
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Hang, Bo, and Chenna, Ahmed. NNA-DNA adducts as biomarkers for detecting exposure to thirdhand smoke. United States: N. p., 2020. Web.
Hang, Bo, & Chenna, Ahmed. NNA-DNA adducts as biomarkers for detecting exposure to thirdhand smoke. United States.
Hang, Bo, and Chenna, Ahmed. Tue . "NNA-DNA adducts as biomarkers for detecting exposure to thirdhand smoke". United States. https://www.osti.gov/servlets/purl/1632461.
@article{osti_1632461,
title = {NNA-DNA adducts as biomarkers for detecting exposure to thirdhand smoke},
author = {Hang, Bo and Chenna, Ahmed},
abstractNote = {NNA-derived specific adducts represent an integrated biomarker of exposure to thirdhand smoke (THS) as NNA is unique to THS. The NNA-dG covalent binding adduct could serve as such a biomarker, and play a role in identifying individuals exposed to THS, thus providing critical information for early detection and prevention.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 21 00:00:00 EST 2020},
month = {Tue Jan 21 00:00:00 EST 2020}
}

Works referenced in this record:

Thirdhand smoke causes DNA damage in human cells
journal, March 2013


8-Oxo-2′-deoxyguanosine as a biomarker of tobacco-smoking-induced oxidative stress
journal, August 2012


Tobacco-Specific Nitrosamine Detection Assays and Reagents
patent-application, February 2005


Formation of carcinogens indoors by surface-mediated reactions of nicotine with nitrous acid, leading to potential thirdhand smoke hazards
journal, February 2010