Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide
Abstract
Disclosed is a method to make N-acetyl-p-aminophenol. The method includes steps for converting biomass-derived p-hydroxybenzoates to p-hydroxybenzamide, then to p-aminophenol; and then N-acetylating the p-aminophenol.
- Inventors:
- Issue Date:
- Research Org.:
- Wisconsin Alumni Research Foundation, Madison, WI (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1568317
- Patent Number(s):
- 10286504
- Application Number:
- 15/914,597
- Assignee:
- Wisconsin Alumni Research Foundation (Madison, WI)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B23 - MACHINE TOOLS B23P - OTHER WORKING OF METAL
B - PERFORMING OPERATIONS B60 - VEHICLES IN GENERAL B60K - ARRANGEMENT OR MOUNTING OF PROPULSION UNITS OR OF TRANSMISSIONS IN VEHICLES
- DOE Contract Number:
- FC02-07ER64494
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 03/07/2018
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Ralph, John, Karlen, Steven, and Mobley, Justin. Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide. United States: N. p., 2019.
Web.
Ralph, John, Karlen, Steven, & Mobley, Justin. Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide. United States.
Ralph, John, Karlen, Steven, and Mobley, Justin. Tue .
"Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide". United States. https://www.osti.gov/servlets/purl/1568317.
@article{osti_1568317,
title = {Synthesis of paracetamol (acetaminophen) from biomass-derived p-hydroxybenzamide},
author = {Ralph, John and Karlen, Steven and Mobley, Justin},
abstractNote = {Disclosed is a method to make N-acetyl-p-aminophenol. The method includes steps for converting biomass-derived p-hydroxybenzoates to p-hydroxybenzamide, then to p-aminophenol; and then N-acetylating the p-aminophenol.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue May 14 00:00:00 EDT 2019},
month = {Tue May 14 00:00:00 EDT 2019}
}
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Works referenced in this record:
Process for the preparation of N-acetyl-P-aminophenol
patent, January 1986
- Sathe, Sharad S.
- US Patent Document 4,565,890
Purification of p-aminophenol compositions and direct conversion to N-acetyl-p-aminophenol
patent, October 1992
- Dunn, Thomas J.; Jovanovic, Vojko B.
- US Patent Document 5,155,269
Production of acetaminophen
patent, October 1992
- Fritch, John R.; Fruchey, O. Stanley; Horlenko, Theodore
- US Patent Document 5,155,273