Modular, micro-scale, optical array and biodetection system
Abstract
A modular, micro-scale, optical array and biodetection device for quantifying fluorescence intensities of a plurality of substantially separated, and dimensionally uniform elements of a bioarray that are located at known positions on a plain support includes a light guide that directs bioarray illumination light from a respective light source to opposing sides of the plain support. An optical module collecting light individually from the bioarray elements includes an optical member, a filter, and a sensor, such as a CCD chip. The optical member collects and transfers emitted light from the bioarray elements via the filter to the sensor. The filter transfers light from the elements having a predefined wavelength spectrum and blocks light outside the predefined wavelength spectrum. The sensor receives transferred light from the elements and produces a signal corresponding to respective elements of the bioarray.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1531573
- Patent Number(s):
- 7463353
- Application Number:
- 11/444,241
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-31-109-ENG-38
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2006-05-31
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 42 ENGINEERING; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Yershov, Gennadiy M. Modular, micro-scale, optical array and biodetection system. United States: N. p., 2008.
Web.
Yershov, Gennadiy M. Modular, micro-scale, optical array and biodetection system. United States.
Yershov, Gennadiy M. Tue .
"Modular, micro-scale, optical array and biodetection system". United States. https://www.osti.gov/servlets/purl/1531573.
@article{osti_1531573,
title = {Modular, micro-scale, optical array and biodetection system},
author = {Yershov, Gennadiy M.},
abstractNote = {A modular, micro-scale, optical array and biodetection device for quantifying fluorescence intensities of a plurality of substantially separated, and dimensionally uniform elements of a bioarray that are located at known positions on a plain support includes a light guide that directs bioarray illumination light from a respective light source to opposing sides of the plain support. An optical module collecting light individually from the bioarray elements includes an optical member, a filter, and a sensor, such as a CCD chip. The optical member collects and transfers emitted light from the bioarray elements via the filter to the sensor. The filter transfers light from the elements having a predefined wavelength spectrum and blocks light outside the predefined wavelength spectrum. The sensor receives transferred light from the elements and produces a signal corresponding to respective elements of the bioarray.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 09 00:00:00 EST 2008},
month = {Tue Dec 09 00:00:00 EST 2008}
}
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