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Title: Self-assembly of peptide-amphiphile nanofibers under physiological conditions

Abstract

Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions.

Inventors:
; ;
Issue Date:
Research Org.:
Northwestern Univ., Evanston, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1531556
Patent Number(s):
7371719
Application Number:
10/368,517
Assignee:
Northwestern University (Evanston, IL)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
F49620-00-1-0283/P01; FG02-00ER45810; DMR-9996253
Resource Type:
Patent
Resource Relation:
Patent File Date: 2003-02-18
Country of Publication:
United States
Language:
English

Citation Formats

Stupp, Samuel I., Hartgerink, Jeffrey D., and Beniash, Elia. Self-assembly of peptide-amphiphile nanofibers under physiological conditions. United States: N. p., 2008. Web.
Stupp, Samuel I., Hartgerink, Jeffrey D., & Beniash, Elia. Self-assembly of peptide-amphiphile nanofibers under physiological conditions. United States.
Stupp, Samuel I., Hartgerink, Jeffrey D., and Beniash, Elia. Tue . "Self-assembly of peptide-amphiphile nanofibers under physiological conditions". United States. https://www.osti.gov/servlets/purl/1531556.
@article{osti_1531556,
title = {Self-assembly of peptide-amphiphile nanofibers under physiological conditions},
author = {Stupp, Samuel I. and Hartgerink, Jeffrey D. and Beniash, Elia},
abstractNote = {Peptide amphiphile compounds, compositions and methods for self-assembly or nanofibrous network formation under neutral or physiological conditions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue May 13 00:00:00 EDT 2008},
month = {Tue May 13 00:00:00 EDT 2008}
}

Works referenced in this record:

Control of Aragonite or Calcite Polymorphism by Mollusk Shell Macromolecules
journal, January 1996


Covalent capture of dynamic hydrogen-bonded assemblies
journal, January 2000


A Simple Two-Step Approach for Introducing a Protected Diaminedithiol Chelator during Solid-Phase Assembly of Peptides
journal, May 2002


Metalloporphyrin Nanotube Fabrication Using Peptide Nanotubes as Templates
journal, December 2001


The phosphodiesterase inhibitor rolipram delivered after a spinal cord lesion promotes axonal regeneration and functional recovery
journal, June 2004


Supramolecular Hydrogels Respond to Ligand−Receptor Interaction
journal, November 2003


Enhancement of Bone Growth by Sustained Delivery of Recombinant Human Bone Morphogenetic Protein-2 in a Polymeric Matrix
journal, December 2001


The deprotection of Lys(Mtt) revisited
journal, June 2000


Control of crystal nucleation by patterned self-assembled monolayers
journal, April 1999


Mapping the heparin-binding sites on type I collagen monomers and fibrils.
journal, June 1994


Self-Assembly of Model Collagen Peptide Amphiphiles
journal, August 2001


Methods and compositions for encapsulation of cells
patent-application, November 2006


Calcium phosphate precipitation on the surface of HA-G-Ti composite under physiologic conditions
journal, January 1994


Nogo-66 receptor antagonist peptide promotes axonal regeneration
journal, May 2002


Structures of biological minerals in dental research
journal, November 2001


Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane.
journal, April 1993


Organoapatites: Materials for artificial bone. III. Biological testing
journal, March 1993


Biomaterials in Tissue Engineering
journal, June 1995


Organoapatites: Materials for artificial bone. II. Hardening reactions and properties
journal, March 1993


Bioactivation of Metal Oxide Surfaces. 1. Surface Characterization and Cell Response
journal, September 1999


Mechanisms of Disease: what factors limit the success of peripheral nerve regeneration in humans?
journal, August 2006


Protein Design and Phage Display
journal, October 2001


Mimicry of natural material designs and processes
journal, June 1995


Polymeric system for dual growth factor delivery
journal, November 2001


Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins
book, January 1986


Model Studies of the Effect of Orthophospho- l -serine on Biological Mineralization
journal, February 2001


Formation of Helical Super Structure from Single-Walled Bilayers by Amphiphiles with Oligo-L-Glutamic Acid-Head Group
journal, October 1984


Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells
journal, February 2002


Directional Neurite Outgrowth and Axonal Differentiation of Embryonic Hippocampal Neurons are Promoted by a Neurite Outgrowth Domain of the B2‐Chain of Laminin
journal, June 1996


The basic science of gene therapy
journal, May 1993


Fast precipitation of calcium phosphate layers on titanium induced by simple chemical treatments
journal, January 1997


X‐ray photoelectron spectroscopy applied to gold‐decorated mineral standards of biological interest
journal, April 1984


Control of crystal phase switching and orientation by soluble mollusc-shell proteins
journal, May 1996


Design strategies in mineralized biological materials
journal, January 1997


Tissue engineering
journal, May 1993


Tissue factor methods and compositions for coagulation and tumor treatment
patent, December 2000


Self-assembling properties of synthetic peptidic lipids
journal, April 1993


Allogeneic Mesenchymal stem Cells Regenerate bone in a Critical-Sized Canine Segmental Defect
journal, January 2003


Controllable Orientation of the Peptide-Based Surfactant at Air-Water Interface
journal, May 1997


Soft-Tissue Augmentation with Injectable Alginate and Syngeneic Fibroblasts
journal, January 2000


Plasma sprayed coatings of hydroxylapatite
journal, December 1987


Surface coating spatially controlled patterns
patent, February 2005


Encapsulation of nanotubes via self-assembled nanostructures
patent, May 2005


Control of self-assembling oligopeptide matrix formation through systematic variation of amino acid sequence
journal, January 2002


THE MATERIAL BONE: Structure-Mechanical Function Relations
journal, August 1998


Osteoblast and Chrondrocyte Proliferation in the Presence of Alumina And Titania Nanoparticles
journal, June 2002


Hydroxylapatite coating of porous implants improves bone ingrowth and interface attachment strength
journal, August 1992


Structural arrangements at the interface between plasma sprayed calcium phosphates and bone
journal, June 1994


The Specification of Dorsal cell Fates in the Vertebrate Central Nervous System
journal, March 1999


Transforming Growth Factor-β Induction of Smooth Muscle Cell Phenotpye Requires Transcriptional and Post-transcriptional Control of Serum Response Factor
journal, December 2001


The ultrastructure of the plasma-sprayed hydroxyapatite–bone interface predisposing to bone bonding
journal, February 2002


Bone marrow cells regenerate infarcted myocardium
journal, April 2001


Self-Assembled Peptide Amphiphile Nanofibers Conjugated to MRI Contrast Agents
journal, January 2005


Development of fibrin derivatives for controlled release of heparin-binding growth factors
journal, April 2000


Biomimetic coatings on titanium: a crystal growth study of octacalcium phosphate
journal, June 2001


Cell seeding in porous transplantation devices
journal, January 1993


Surface modifications for enhanced epithelialization
patent-application, January 2002


Biodegradable, Elastic Shape-Memory Polymers for Potential Biomedical Applications
journal, April 2002


Properties of the (DSS) n triplet repeat domain of rat dentin phosphophoryn
journal, January 1998


Monoclonal Antibody Recognition of Histidine-Rich Peptide Encapsulated Nanoclusters
journal, March 2002


The Process of Physical Weakening and Dissolution of the HA-coated Implant in Bone and Soft Tissue
journal, June 1998


Self-assembling peptide amphiphile nanofiber matrices for cell entrapment
journal, July 2005


The effect of hydroxyapatite coating on bone growth into porous titanium alloy implants
journal, March 1989


Osteogenic Activity of the Fourteen Types of Human bone Morphogenetic Proteins (Bmps)
journal, January 2003


Microencapsulated iNOS‐expressing cells cause tumor suppression in mice
journal, December 2001


Progenitor Cell Biology: Implications for Neural Regeneration
journal, July 1999


Molecular monolayer rods and tubules made of .alpha.-(L-lysine),.omega.-(amino) bolaamphiphiles
journal, February 1993


Recent advances in ZnO materials and devices
journal, March 2001


Modulation of the growth and guidance of rat brain stem neurons using patterned extracellular matrix proteins
journal, March 2001


Bonelike apatite coating on organic polymers: novel nucleation process using sodium silicate solution
journal, May 1999


Bone structure: from ångstroms to microns
journal, February 1992


Heparin-induced Self-association of Fibroblast Growth Factor-2: EVIDENCE FOR TWO OLIGOMERIZATION PROCESSES
journal, June 1997


Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord
journal, December 1999


Miracles and molecules—progress in spinal cord repair
journal, October 2002


Hierarchical self-assembly of chiral rod-like molecules as a model for peptide  -sheet tapes, ribbons, fibrils, and fibers
journal, October 2001


Multilineage Potential of Adult Human Mesenchymal Stem Cells
journal, April 1999


Structure and design of polymeric surfactant-based drug delivery systems
journal, June 2001


In vitro and in vivo degradation of porous poly(dl-lactic-co-glycolic acid) foams
journal, September 2000


Can One Derive the Conformational Preference of a β-Peptide from Its CD Spectrum?
journal, November 2002


Wound tissue can utilize a polymeric template to synthesize a functional extension of skin
journal, January 1982


General approach to the synthesis of short .alpha.-helical peptides
journal, November 1991


Molecular Modelling of a Multiphosphorylated Sequence Motif Bound to Hydroxyapatite Surfaces
journal, February 2000


Neurotrophins: Roles in Neuronal Development and Function
journal, March 2001


Engineering growing tissues
journal, September 2002


Self-assembly and mineralization of peptide-amphiphile nanofibers
patent-application, January 2004


New coupling reagents in peptide chemistry
journal, January 1989


Self-Assembly and Mineralization of Peptide-Amphiphile Nanofibers
journal, November 2001


Chemical Attachment of Polystyrene- block -poly(methacrylic acid) Micelles on a Silicon Nitride Surface
journal, January 1996


Self-Assembly of Dendron Rodcoil Molecules into Nanoribbons
journal,  


Minimal Lipidation Stabilizes Protein-Like Molecular Architecture
journal, October 1998


Bone marrow stromal cells enhance differentiation of cocultured neurosphere cells and promote regeneration of injured spinal cord
journal, May 2003


Stem cell biology of the central nervous system
journal, August 2002


Self-assembly and applications of biomimetic and bioactive peptide-amphiphiles
journal, January 2006


Comparison of cultured and uncultured keratinocytes seeded into a collagen–GAG matrix for skin replacements
journal, March 1999


Molecular Manipulation of Microstructures: Biomaterials, Ceramics, and Semiconductors
journal, August 1997


Physicochemical characterization and biological activity of a glycoglycerolipid from Mycoplasma fermentans
journal, August 2003


Biomimetic Mineralization of Collagen by Combined Fibril Assembly and Calcium Phosphate Formation
journal, October 1999


Organoapatites: Materials for artificial bone. I. Synthesis and microstructure
journal, February 1992


Synthetic lipidation of peptides and amino acids: monolayer structure and properties.
journal, September 1995


Vascularized Collagen-Glycosaminoglycan Matrix Provides a Dermal Substrate and Improves Take of Cultured Epithelial Autografts
journal, January 1998


Angiopoietin-1 and Its Receptor Tie-2 Participate in the Regulation of Capillary-like Tubule Formation and Survival of Endothelial Cells
journal, November 1999


Nanostructured Polymer/Nanophase Ceramic Composites Enhance Osteoblast and Chondrocyte Adhesion
journal, October 2002


Novel biomaterials for drug delivery
journal, September 2001


Differentiation of human embryonic germ cells
patent, May 2003


Formation and Structure of Self-Assembled Monolayers
journal, January 1996


Modulation of neural network activity by patterning
journal, September 2001


Progress toward a Peptidomimetic of Laminin-Derived Pentapeptide YIGSR:  Synthesis of the Unique Tricyclic Core Structure
journal, August 2002


System and method for computer-based automatic essay scoring
patent, January 2001


Surfactant peptide nanostructures, and uses thereof
patent-application, September 2003


Spatial organization and patterning of gold nanoparticles on self-assembled biolipid tubular templates
journal, January 1996


Wetting of poly(l-lactic acid) and poly(dl-lactic-co-glycolic acid) foams for tissue culture
journal, January 1994


Trifluoroacetate, a contaminant in purified proteins, inhibits proliferation of osteoblasts and chondrocytes
journal, November 1999


Dentifrice
patent, July 1992


Optical processes in ZnO
journal, December 1995


Diverse mechanisms of osteoblast spreading on hydroxyapatite and titanium
journal, June 2000


Self-assembly of peptide-amphiphile nanofibers under physiological conditions
patent-application, January 2004


cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury
journal, May 2004


Organization of Peptide Nanotubes into Macroscopic Bundles
journal, November 2001

  • Matsui, Hiroshi; Douberly, Gary E.
  • Langmuir, Vol. 17, Issue 25, p. 7918-7922
  • URL: 10.1021/la010910+

Synthesis and Physicochemical Characterization of Cyclic Laminin Related Peptides
journal, June 1998


Organization of 'nanocrystal molecules' using DNA
journal, August 1996


In Vitro Models of Vasculogenesis and Angiogenesis
journal, April 2001


Intralayer hydrogen-bond-directed self-assembly of nano-fibers from dicarboxylic valylvaline bolaamphiphiles
journal, January 1998


Regulation of β-Sheet Structures within Amyloid-Like β-Sheet Assemblage from Tripeptide Derivatives
journal, December 1998


Calcium Phosphate Phase Identification Using XPS and Time-of-Flight Cluster SIMS
journal, January 1999


Conformational behavior of ionic self-complementary peptides
journal, January 2000


Octacalcium phosphate. 3. Infrared and Raman vibrational spectra
journal, October 1993


Phage Display
journal, April 1997


Giant Wormlike Rubber Micelles
journal, February 1999


Excitonic ultraviolet laser emission at room temperature from naturally made cavity in ZnO nanocrytal thin films
journal, November 1998


Design of Peptides with High Affinities for Heparin and Endothelial Cell Proteoglycans
journal, March 2000


Therapeutic compounds comprised of anti-Fc receptor antibodies
patent, August 2001


Effects of GDNF on Axotomized Sensory and Motor Neurons in Adult Rats
journal, June 1997


Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine
journal, December 1995


In VitroChondrogenesis of Bone Marrow-Derived Mesenchymal Progenitor Cells
journal, January 1998


Selection of peptides with semiconductor binding specificity for directed nanocrystal assembly
journal, June 2000


Fabrication of Nanofibers with Uniform Morphology by Self-Assembly of Designed Peptides
journal, June 2004


The Carboxyl-terminal Domain(111165) of Vascular Endothelial Growth Factor Is Critical for Its Mitogenic Potency
journal, March 1996


Controlled release of fibroblast growth factors and heparin from photocrosslinked chitosan hydrogels and subsequent effect onin vivo vascularization
journal, February 2003


Organization of hydroxyapatite crystals within collagen fibrils
journal, October 1986


Determination of protein secondary structure by Fourier transform infrared spectroscopy: A critical assessment
journal, January 1993


Electrophysiological recordings of patterned rat brain stem slice neurons
journal, August 2002


Structural Study of Langmuir Monolayers Containing Lipidated Poly(ethylene glycol) and Peptides
journal, October 2001


Synthetic Bilayer Membranes: Molecular Design, Self-Organization, and Application
journal, June 1992


TEM-EDX study of mechanism of bonelike apatite formation on bioactive titanium metal in simulated body fluid
journal, January 2001


Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof
patent-application, September 2005


Excitonic gain and stimulated ultraviolet emission in nanocrystalline zinc-oxide powder
journal, October 2000


Phospholipid vesicles as a model system for biomineralization
journal, December 1986


Methods and materials for nanocrystalline surface coatings and attachment of peptide amphiphile nanofibers thereon
patent-application, December 2004


Derivatives of GLP-1 analogs
patent, October 2002


Electrochemical Nucleation of Gold Nanoparticles in a Polymer Film at a Liquid−Liquid Interface
journal, February 2005


Hydrophilicity of Polar and Apolar Domains of Amphiphiles
journal, September 2000


Control and Design Principles in Biological Mineralization
journal, February 1992


Self-Assembling Amphiphiles for Construction of Protein Molecular Architecture
journal, January 1996


Noncovalent Formation of Polyglycine II-Type Structure by Hexagonal Self-Assembly of Linear Polymolecular Chains
journal, July 1997


Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
journal, October 2000


Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds
journal, June 2000


Nanostructured Ceramics for Biomedical Implants
journal, July 2002


Methods for automated essay analysis
patent-application, October 2002


pH as a Trigger of Peptide β-Sheet Self-Assembly and Reversible Switching between Nematic and Isotropic Phases
journal, August 2003


Presentation and Recognition of Biotin on Nanofibers Formed by Branched Peptide Amphiphiles
journal, February 2005


Human dentin phosphophoryn nucleotide and amino acid sequence
journal, December 1998


Rapidly recovering hydrogel scaffolds from self-assembling diblock copolypeptide amphiphiles
journal, May 2002


Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction
journal, October 1981


Improving cell encapsulation through size control
journal, January 2002


Peptide and Protein Presenting Materials for Tissue Engineering
journal, January 2004


Characterization of Peptide−Amphiphiles Possessing Cellular Activation Sequences
journal, May 2003


Structure and Dynamics of Peptide−Amphiphiles Incorporating Triple-Helical Proteinlike Molecular Architecture
journal, February 1999


Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily
journal, December 2002


Microlaser made of disordered media
journal, May 2000


Covalent Attachment of Novel Poly(ethylene glycol)−Poly( dl -lactic acid) Copolymeric Micelles to TiO 2 Surfaces
journal, January 2002


Biomimetic Synthesis of Macroscopic-Scale Calcium Carbonate Thin Films. Evidence for a Multistep Assembly Process
journal, November 1998


Hydrogels for Tissue Engineering
journal, July 2001


Left-Handed Helical Ribbon Intermediates in the Self-Assembly of a β-Sheet Peptide
journal, April 2002


Synthesis of peptidylglycophospholipids, novel derivatives of muramyl-dipeptide
journal, January 1981


PDMS device for patterned application of microfluids to neuronal cells arranged by microcontact printing
journal, January 2002


Self-assembled peptide-amphiphiles & self-assembled peptide nanofiber networks presenting multiple signals
patent-application, December 2005


Interactions between acidic proteins and crystals: stereochemical requirements in biomineralization.
journal, June 1985


Protein Tubule Immobilization on Self-Assembled Monolayers on Au Substrates
journal, September 2001


Microencapsulated islets as bioartificial endocrine pancreas
journal, November 1980


Method and system for topical segmentation, segment significance and segment function
patent, October 2002


Biomimetic coprecipitation of calcium phosphate and bovine serum albumin on titanium alloy
journal, January 2001


Design of an artificial four-helix bundle metalloprotein via a novel ruthenium(II)-assisted self-assembly process
journal, May 1992


Receptor binding, internalization, and retrograde transport of neurotrophic factors
journal, July 2001


A surface-modified functional liposome capable of binding to cell membranes
journal, January 1999


Nucleation and inhibition of hydroxyapatite formation by mineralized tissue proteins
journal, July 1996


Biodegradation and biocompatibility of PLA and PLGA microspheres
journal, October 1997


Spinal Axon Regeneration Induced by Elevation of Cyclic AMP
journal, June 2002


Microcontact Printing for Precise Control of Nerve Cell Growth in Culture
journal, February 1999


Scaffolding of Polymers by Supramolecular Nanoribbons
journal, February 2002


Stable macroscopic membranes formed by self-assembly of amphiphilic peptides and uses therefor
patent, September 1997


Neural Stem and Progenitor Cells: A Strategy for Gene Therapy and Brain Repair
journal, April 1998


Injection molding of chondrocyte/alginate constructs in the shape of facial implants
journal, January 2001


Fabrication of novel biomaterials through molecular self-assembly
journal, September 2003


Calcium phosphate plasma-sprayed coatings and their stability: Anin vivo study
journal, August 1994


Primate embryonic stem cells
patent, December 1998


Repair of bone defects using synthetic mimetics of collagenous extracellular matrices
journal, April 2003


Endothelial cell–mediated type I collagen gel contraction is regulated by hemin
journal, August 2000


Therapeutic Interventions Following Mammalian Spinal Cord Injury
journal, May 2001


Progress toward human gene therapy
journal, June 1989


Covalent Attachment of Cell-Adhesive, (Arg-Gly-Asp)-Containing Peptides to Titanium Surfaces
journal, September 1998


Self-assembly of poly(ethylene glycol)-based block copolymers for biomedical applications
journal, February 2001


Room-Temperature Ultraviolet Nanowire Nanolasers
journal, June 2001


Endothelial cell-derived heparan sulfate binds basic fibroblast growth factor and protects it from proteolytic degradation.
journal, August 1988


Amphiphilic macrocyclic derivatives and their analogues
patent-application, May 2003


Crystal Structure of a Ternary FGF-FGFR-Heparin Complex Reveals a Dual Role for Heparin in FGFR Binding and Dimerization
journal, September 2000


Injectable Alginate Seeded with Chondrocytes as a Potential Treatment for Vesicoureteral Reflux
journal, August 1993


Biomimetic Growth of Hydroxyapatite on Gelatin Films Doped with Sodium Polyacrylate
journal, December 2000


Structures, function and applications of amphiphilic peptides
journal, November 2002


Covalent linkage of a synthetic peptide to a fluorescent phospholipid and its incorporation into supported phospholipid monolayers
journal, April 1984


The low temperature formation of octacalcium phosphate
journal, September 1993


Tissue engineering: Current state of clinical application
journal, January 2003


Oriented growth of phosphates on polycrystalline titanium in a process mimicking biomineralization
journal, November 1999


Engineering of peptide β-sheet nanotapes
journal, January 1997


Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials
journal, April 2002


Conformation of heparin studied with macromolecular hydrodynamic methods and X-ray scattering
journal, August 2003


Internucleobase-Interaction-Directed Self-Assembly of Nanofibers from Homo- and Heteroditopic 1, ω -Nucleobase Bolaamphiphiles
journal, June 2001


Isolation, Characterization, and use of Stem Cells from the CNS
journal, March 1995


Nitric Oxide and Apoptosis: Another Paradigm for the Double-Edged Role of Nitric Oxide
journal, August 1997


Lipopeptide stabilized microbubbles as diagnostic/therapeutic agents
patent, April 2003


Three-dimensional ordered distribution of crystals in turkey tendon collagen fibers.
journal, December 1989


Nanoscale Clustering of RGD Peptides at Surfaces Using Comb Polymers. 1. Synthesis and Characterization of Comb Thin Films
journal, March 2001


Self-assembling Peptide Amphiphiles and Related Methods for Growth Factor Delivery
patent-application, September 2005


Self-Assembling Amphiphilic Siderophores from Marine Bacteria
journal, February 2000


Induction of protein-like molecular architecture by self-assembly processes
journal, January 1999


False resurrections: Distinguishing regenerated from spared axons in the injured central nervous system
journal, March 2003


Process for nucleation of ceramics and product thereof
patent, November 1999


Discourse parsing and summarization
patent-application, April 2002


Template mineralization of self-assembled anisotropic lipid microstructures
journal, July 1993


Sequence and structure of D-glyceraldehyde 3-phosphate dehydrogenase from Bacillus stearothermophilus
journal, March 1977


In vitro rapid organization of endothelial cells into capillary-like networks is promoted by collagen matrices.
journal, November 1983


Physicochemical aspects of drug delivery and release from polymer-based colloids
journal, March 2000


Self-Assembly of a β-Sheet Protein Governed by Relief of Electrostatic Repulsion Relative to van der Waals Attraction
journal, December 2000


Modulation of cell adhesion by modification of titanium surfaces with covalently attached self-assembled monolayers
journal, October 1990


Assembly of Nanoparticles into Hollow Spheres Using Block Copolypeptides
journal, June 2002


Chondroitinase ABC promotes functional recovery after spinal cord injury
journal, April 2002


Vacuum ultraviolet circular dichroism of protected homooligomers derived from L-leucine
journal, March 1977


Aggregation behavior of synthetic peptide lipids with arginine in aqueous solution and construction of a vitamin B12 artificial enzyme
journal, September 2000


Random laser action in ZnO
journal, August 2000


Solid-state foaming of titanium by superplastic expansion of argon-filled pores
journal, May 2001


Seeding Neural Stem Cells on Scaffolds of PGA, PLA, and Their Copolymers
book, January 2002


Structure of the stable and metastable ripple phase of dipalmitoylphosphatidylcholine
journal, January 1996


Chapter 17 Spinal cord contusion models
book, January 2002


Vacuum ultraviolet circular dichroism of .beta.-forming alkyl oligopeptides
journal, June 1976


Alginate type and RGD density control myoblast phenotype
journal, February 2002


Influence of monosaccharides and related molecules on the morphology of hydroxyapatite
journal, October 1993


Self-Supporting Elastic Film without Covalent Linkages as a Hierarchically Integratedβ-Sheet Assembly
journal, November 2003


Myogenic Expression of Mesenchymal Stem Cells within Myotubes of mdx Mice in Vitro and in Vivo
journal, December 1995


Self-Assembly of a Designed Protein Polymer into β-Sheet Fibrils and Responsive Gels
journal, April 2003


Computed circular dichroism spectra for the evaluation of protein conformation
journal, October 1969


In Vitro Gene Transfection Using Dendritic Poly( l -lysine)
journal, May 2002


Effects of Ischemia on Ulcer Wound Healing: A New Model in the Rabbit Ear
journal, January 1990


Biomineralization: the form(id)able part of bioinorganic chemistry! *
journal, January 1997


Molecular self-assembly of surfactant-like peptides to form nanotubes and nanovesicles
journal, April 2002


Nanostructured Polymer Duplexes via the Covalent Casting of 1-Dimensional H-Bonding Motifs:  A New Strategy for the Self-Assembly of Macromolecular Precursors
journal, May 2000


Aggregation of Polypeptide-Based Amphiphiles in Water
journal, February 2001


Method and system for verifying accuracy of spelling and grammatical composition of a document
patent, July 2000


Coating of Surfaces with Stabilized Reactive Micelles from Poly(ethylene glycol)−Poly( dl -lactic acid) Block Copolymer
journal, August 1999


Mechanical Testing of Electrophoretically Deposited Hydroxyapatite
conference, September 2013


Multiblock biodegradable hydrogels for drug delivery and tissue treatment
patent, March 2001


Axons from CNS neurones regenerate into PNS grafts
journal, March 1980


Bioactive nanocrystalline sol-gel hydroxyapatite coatings
journal, January 1999


The shear strength and the failure mode of plasma-sprayed hydroxyapatite coating to bone: The effect of coating thickness
journal, October 1993


Poly(amino acid) adhesive tissue grafts
patent, March 1998


Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule
journal, May 1984


Protein-based signaling systems in tissue engineering
journal, October 2003


Modification of surfaces by covalent attachment of polymer micelles
journal, April 1999


CdS mineralization of hexagonal, lamellar, and cubic lyotropic liquid crystals
journal, February 1999


Transmission Spectra of ZnO Single Crystals
journal, January 1968


A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device
journal, March 1987


Self-assembled peptide fibers from valylvaline bola-amphiphiles by a parallel β-sheet network
journal, July 2000


Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection
journal, June 1996


Microcontact Printing: A Versatile Technique for the Study of Synaptogenic Molecules
journal, May 2002


Inhibition of Axon Growth by Oligodendrocyte Precursor Cells
journal, May 2002


Two-Dimensional Arrays of Self-Assembled Gold and Sulfur-Containing Fullerene Nanoparticles
journal, April 2002


Random Laser Action in Semiconductor Powder
journal, March 1999


Structure-activity study of a laminin α1 chain active peptide segment Ile-Lys-Val-Ala-Val (IKVAV)
journal, May 1995


Viability, adhesion, and bone phenotype of osteoblast-like cells on polyelectrolyte multilayer films: Viability, Adhesion, and Bone Phenotype
journal, March 2002


Approaching Exponential Growth with a Self-Replicating Peptide
journal, June 2002


Flow oriented linear dichroism to probe protein orientation in membrane environments
journal, January 2002


Self-complementary oligopeptide matrices support mammalian cell attachment
journal, December 1995


Thermotropic mesophases of ionic amphiphiles: II. Ionic amphiphiles in aqueous media
journal, November 1994


Biomaterials in Drug Delivery and Tissue Engineering:  One Laboratory's Experience
journal, February 2000


Effect of chirality on the formation of tubules from glycolipidic amphiphiles
journal, March 1996


Composition and method for self-assembly and mineralizatin of peptide amphiphiles
patent-application, July 2006


Polysaccharide strong and weak gels
journal, August 1993


Self-Assembly Combining Two Bioactive Peptide-Amphiphile Molecules into Nanofibers by Electrostatic Attraction
journal, June 2003


Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix
journal, October 2000


A method to attach lectins to the surface of spermine alginate microcapsules based on the avidin biotin interaction
journal, January 1996


Hydroxy- and fluorapatite films on Ti alloy substrates: Sol-gel preparation and characterization
journal, July 2001


Molecular modeling of protein-glycosaminoglycan interactions.
journal, January 1989


Sustained release of basic fibroblast growth factor and angiogenesis in a novel covalently crosslinked gel of heparin and alginate
journal, January 2001


Alginate hydrogels as synthetic extracellular matrix materials
journal, January 1999


A general method for preparation of peptides biotinylated at the carboxy terminus
journal, April 1992


The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro
journal, July 2004


Effect of proteoglycans on in vitro hydroxyapatite formation
journal, December 1979


Encapsulation of nanotubes via self-assembled nanostructures
patent-application, February 2004


Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
journal, February 2004


Peptide scaffold encapsulation of tissue cells and uses thereof
patent-application, October 2002


Semiconductor Clusters, Nanocrystals, and Quantum Dots
journal, February 1996


Neural Tissue Engineering: Strategies for Repair and Regeneration
journal, August 2003


Spectroscopic investigation on gel-forming ?-sheet assemblage of peptide derivatives
journal, October 2003


Solid-phase synthesis of C-terminal modified peptides
journal, January 2003


Mechanism for the Enhanced Diffusion of Charged Oxygen Ions in SiO 2
journal, February 2001


Alginate based new materials
journal, August 1997


Dicarboxylic Oligopeptide Bolaamphiphiles:  Proton-Triggered Self-Assembly of Microtubes with Loose Solid Surfaces
journal, September 1998


The Deposition of Calcium Phosphates within Polyelectrolyte Multilayer Films
journal, May 2003


Selective Adhesion of Endothelial Cells to Artificial Membranes with a Synthetic RGD-Lipopeptide
journal, March 2001


Block copolymers for multifunctional self-assembled systems
patent-application, March 2003


Functional Arteries Grown in Vitro
journal, April 1999


Highly Porous Polymer Matrices as a Three-Dimensional Culture System for Hepatocytes
journal, September 1997


Hydroxyapatite-Coated Titanium for Orthopedic Implant Applications
journal, January 1988


Cross-Linking Exogenous Bifunctional Peptides into Fibrin Gels with Factor XIIIa
journal, January 1999


    Works referencing / citing this record:

    Composition and method for self-assembly and mineralization of peptide-amphiphiles
    patent, February 2012


    Peptide amphiphiles having improved solubility and methods of using same
    patent, December 2011


    Medical devices having activated surfaces
    patent, January 2019


    Adhesive barbed filament
    patent, October 2017


    Targeted therapy for the prevention of restenosis in the cardiovascular system
    patent, December 2016


    Medical devices incorporating functional adhesives
    patent, January 2017


    Self-assembling peptide amphiphiles and related methods for growth factor delivery
    patent, June 2009


    Branched amphipathic oligo-peptides that self-assemble into vesicles
    patent, November 2014


    Medical devices having activated surfaces
    patent, December 2016


    Medical device with inflammatory response-reducing coating
    patent, November 2014


    Self-assembling peptides and their use in the formation of hydrogels
    patent, May 2014


    Composition and method for self-assembly and mineralization of peptide amphiphiles
    patent, June 2009


    Medical devices having activated surfaces
    patent, March 2015


    Aligned nanofibers and related methods of use
    patent, December 2016


    Synthesis and self-assembly of ABC triblock bola peptide amphiphiles
    patent, March 2010


    Amphiphilic compounds and self-assembling compositions made therefrom
    patent, February 2015


    Hetero-assembling, tunable, and injectable hydrogels for cell encapsulation
    patent, July 2016


    Bioadhesive composition formed using click chemistry
    patent, October 2011


    Crosslinked fibers and method of making same by extrusion
    patent, February 2014


    Functionalized surgical adhesives
    patent, March 2015


    Medical devices incorporating functional adhesives
    patent, September 2013


    Self-assembling peptide amphiphiles and related methods for growth factor delivery
    patent, March 2012


    Self-assembly and mineralization of peptide-amphiphile nanofibers
    patent, November 2010


    Medical devices with an activated coating
    patent, March 2016


    Functionalized adhesive medical gel
    patent, March 2014


    Anti-angiogenic molecules, nanostructures and uses thereof
    patent, October 2015


    Medical devices having activated surfaces
    patent, January 2017


    Aligned nanofibers and related methods of use
    patent, July 2014


    Method of forming a medical device on biological tissue
    patent, August 2013


    Co-assembly method and co-assembled structures made thereby
    patent, November 2011


    Peptide-based scaffolds for cartilage regeneration and methods for their use
    patent, May 2013


    Medical devices with an activated coating
    patent, December 2016


    Crosslinked fibers and method of making same using UV radiation
    patent, December 2016


    Medical device with predefined activated cellular integration
    patent, October 2014


    Self-assembly and mineralization of peptide-amphiphile nanofibers
    patent, February 2009


    Hetero-assembled hydrogels
    patent, April 2015


    Compounds and medical devices activated with solvophobic linkers
    patent, March 2015


    Self-assembly of peptide-amphiphile nanofibers under physiological conditions
    patent, June 2010


    Crosslinked fibers and method of making same by extrusion
    patent, August 2016


    Self-assembly of peptide-amphiphile nanofibers under physiological conditions
    patent, November 2011


    Self-assembling peptide amphiphiles and related methods for growth factor delivery
    patent, November 2013


    Compounds and medical devices activated with solvophobic linkers
    patent, December 2015


    Medical devices incorporating functional adhesives
    patent, December 2016


    Self-assembling peptide amphiphiles
    patent, February 2012


    Self-assembling peptide amphiphiles for tissue engineering
    patent, February 2012


    Medical devices incorporating functional adhesives
    patent, August 2014