Electrospray ionizer for mass spectrometry of aerosol particles
Abstract
A device and method are disclosed to apply ESI-based mass spectroscopy to submicrometer and nanometer scale aerosol particles. Unipolar ionization is utilized to charge the particles in order to collect them electrostatically on the tip of a tungsten rod. Subsequently, the species composing the collected particles are dissolved by making a liquid flow over the tungsten rod. This liquid with dissolved aerosol contents is formed into highly charged droplets, which release unfragmented ions for mass spectroscopy, such as time-of-flight mass spectroscopy. The device is configured to operate in a switching mode, wherein aerosol deposition occurs while solvent delivery is turned off and vice versa.
- Inventors:
- Issue Date:
- Research Org.:
- MSP Corporation, Shoreview, MN (United States); Univ. of Minnesota, Minneapolis, MN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1393424
- Patent Number(s):
- 9768005
- Application Number:
- 15/135,132
- Assignee:
- MSP Corporation (Shoreview, MN); Regents of the University of Minnesota (Minneapolis, MN)
- Patent Classifications (CPCs):
-
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- SC0013302
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2016 Apr 21
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 36 MATERIALS SCIENCE
Citation Formats
He, Siqin, Hogan, Chris, Li, Lin, Liu, Benjamin Y. H., Naqwi, Amir, and Romay, Francisco. Electrospray ionizer for mass spectrometry of aerosol particles. United States: N. p., 2017.
Web.
He, Siqin, Hogan, Chris, Li, Lin, Liu, Benjamin Y. H., Naqwi, Amir, & Romay, Francisco. Electrospray ionizer for mass spectrometry of aerosol particles. United States.
He, Siqin, Hogan, Chris, Li, Lin, Liu, Benjamin Y. H., Naqwi, Amir, and Romay, Francisco. Tue .
"Electrospray ionizer for mass spectrometry of aerosol particles". United States. https://www.osti.gov/servlets/purl/1393424.
@article{osti_1393424,
title = {Electrospray ionizer for mass spectrometry of aerosol particles},
author = {He, Siqin and Hogan, Chris and Li, Lin and Liu, Benjamin Y. H. and Naqwi, Amir and Romay, Francisco},
abstractNote = {A device and method are disclosed to apply ESI-based mass spectroscopy to submicrometer and nanometer scale aerosol particles. Unipolar ionization is utilized to charge the particles in order to collect them electrostatically on the tip of a tungsten rod. Subsequently, the species composing the collected particles are dissolved by making a liquid flow over the tungsten rod. This liquid with dissolved aerosol contents is formed into highly charged droplets, which release unfragmented ions for mass spectroscopy, such as time-of-flight mass spectroscopy. The device is configured to operate in a switching mode, wherein aerosol deposition occurs while solvent delivery is turned off and vice versa.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Sep 19 00:00:00 EDT 2017},
month = {Tue Sep 19 00:00:00 EDT 2017}
}
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