Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual

Apel, William A.; Thompson, Vicki S; Lacey, Jeffrey A.; Gentillon, Cynthia A.

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Title: Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual

Abstract

A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample from a plurality of individuals against a protein array including a plurality of proteins. The protein array may include proteins attached to a support in a preselected pattern such that locations of the proteins are known. The biological sample may be contacted with the protein array such that a portion of antibodies in the biological sample reacts with and binds to the proteins forming immune complexes. A statistical analysis method, such as discriminant analysis, may be performed to determine discriminating proteins for distinguishing individuals. Proteins of interest may be used to form a protein array. Such a protein array may be used, for example, to compare a forensic sample from an unknown source with a sample from a known source.

Inventors:: Apel, William A.; Thompson, Vicki S; Lacey, Jeffrey A.; Gentillon, Cynthia A.

Issue Date:: Tue Aug 09 00:00:00 EDT 2016

Research Org.:: Idaho National Laboratory (INL), Idaho Falls, ID (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1290004

Patent Number(s):: 9410965

Application Number:: 12/883,002

Assignee:: Battelle Energy Alliance, LLC (Idaho Falls, ID)

Patent Classifications (CPCs):: G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

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G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
G01N33/6845 - {Methods of identifying protein-protein interactions in protein mixtures}

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DOE Contract Number:: AC07-05ID14517

Resource Type:: Patent

Resource Relation:: Patent File Date: 2010 Sep 15

Country of Publication:: United States

Language:: English

Subject:: 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

Citation Formats


                    Apel, William A., Thompson, Vicki S, Lacey, Jeffrey A., and Gentillon, Cynthia A. Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual.  United States: N. p., 2016. 
        Web.

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                    Apel, William A., Thompson, Vicki S, Lacey, Jeffrey A., & Gentillon, Cynthia A. Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual.  United States.

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                    Apel, William A., Thompson, Vicki S, Lacey, Jeffrey A., and Gentillon, Cynthia A. Tue .  
        "Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual".  United States.  https://www.osti.gov/servlets/purl/1290004.

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@article{osti_1290004,

  title        = {Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual},

  author       = {Apel, William A. and Thompson, Vicki S and Lacey, Jeffrey A. and Gentillon, Cynthia A.},

  abstractNote = {A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample from a plurality of individuals against a protein array including a plurality of proteins. The protein array may include proteins attached to a support in a preselected pattern such that locations of the proteins are known. The biological sample may be contacted with the protein array such that a portion of antibodies in the biological sample reacts with and binds to the proteins forming immune complexes. A statistical analysis method, such as discriminant analysis, may be performed to determine discriminating proteins for distinguishing individuals. Proteins of interest may be used to form a protein array. Such a protein array may be used, for example, to compare a forensic sample from an unknown source with a sample from a known source.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Aug 09 00:00:00 EDT 2016},

  month        = {Tue Aug 09 00:00:00 EDT 2016}

}

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Works referenced in this record:

Marking Instrument
patent, August 1896

Bell, W. J.
US Patent Document 566,558
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/0566558

Assay employing a labeled Fab-fragment ligand complex
patent, November 1980

Schwarzberg, Moshe
US Patent Document 4,235,869
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4235869

Phycobiliprotein fluorescent conjugates
patent, September 1985

Stryer, Lubert; Glazer, Alexander N.
US Patent Document 4,542,104
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4542104

Individual-specific antibody identification methods
patent, November 1989

Francoeur, Ann-Michele
US Patent Document 4,880,750
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/4880750

Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques
patent, August 1993

Sun, Ming; Pfeiffer, Francis R.
US Patent Document 5,238,652
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5238652

Methods of identification employing antibody profiles
patent, December 1993

Francoeur, Ann-Michele
US Patent Document 5,270,167
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5270167

Modified avidin-biotin technique
patent, January 1994

Trojanowski, John Q.; Lee, Virginia Man-Yee
US Patent Document 5,281,521
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5281521

Array of oligonucleotides on a solid substrate
patent, August 1995

Fodor, Stephen P. A.; Pirrung, Michael C.; Read, J. Leighton
US Patent Document 5,445,934
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5445934

Method of detecting and correcting a direction of image data and document image filing system employing the same
patent, November 1995

Kurosu, Yasuo; Masuzaki, Hidefumi; Fujisawa, Hiromichi
US Patent Document 5,471,549
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5471549

Anti-idiotypic monoclonal antibody that induces an immune response against the ganglioside GD.sub.3 and hybridoma producing said antibody
patent, June 1996

Chapman, Paul; Houghton, Alan
US Patent Document 5,529,922
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5529922

Method for detecting an analyte using an electrochemical luminescent transition metal label
patent, July 1996

Siddigi, Iqbal W.; Sternberg, James C.
US Patent Document 5,541,113
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5541113

Active programmable electronic devices for molecular biological analysis and diagnostics
patent, February 1997

Heller, Michael J.; Tu, Eugene
US Patent Document 5,605,662
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5605662

Arrays of materials attached to a substrate
patent, April 1998

Fodor, Stephen P. A.; Stryer, Lubert; Read, J. Leighton
US Patent Document 5,744,305
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5744305

Patterning antibodies on a surface
patent, January 1999

Brizzolara, Robert A.
US Patent Document 5,858,801
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5858801

Method of obtaining small conformationally rigid conopeptides
patent, March 1999

Olivera, Baldomero M.; Hillyard, David R.; Myers, Richard A.
US Patent Document 5,885,780
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5885780

Monoclonal antibodies against human pancreatic islet cells
patent, March 1999

Endl, Josef; Brandt, Michael; Jungfer, Herbert
US Patent Document 5,888,813
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/5888813

Miniaturized cell array methods and apparatus for cell-based screening
patent, August 2000

Taylor, D. Lansing
US Patent Document 6,103,479
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6103479

Method and apparatus for automated image analysis of biological specimens
patent, April 2003

Douglass, James W.; Riding, Thomas J.; Ring, James E.
US Patent Document 6,553,135
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6553135

Method and apparatus for acquiring offset checkshot survey data using tube-wave conversion
patent, July 2003

Krebs, Jerome R.; Chen, Sen-Tsuen
US Patent Document 6,591,193
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6591193

Method and system for extracting data from surface array deposited features
patent, July 2003

Yakhini, Zohar; Enderwick, Cynthia Y.; Delenstarr, Glenda
US Patent Document 6,591,196
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6591196

Aminediols for the treatment of Alzheimer's disease
patent, June 2005

Schostarez, Heinrich J.; Chrusciel, Robert A.
US Patent Document 6,906,104
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6906104

System, method, and computer software product for grid alignment of multiple scanned images
patent, November 2005

Kaushikkar, Shantanu; Patil, Sangita B.
US Patent Document 6,965,704
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6965704

Method, system, and computer code for finding spots defined in biological microarrays
patent, December 2005

Niles, Richard K.; Martens, Christine L.; Foskett, Darach B.
US Patent Document 6,980,677
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6980677

Rapid classification of biological components
patent, January 2006

Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.
US Patent Document 6,989,276
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/6989276

Systems and methods for automated analysis of cells and tissues
patent, May 2007

Rimm, David L.; Camp, Robert L.
US Patent Document 7,219,016
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7219016

Rapid classification of biological components
patent, March 2010

Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.
US Patent Document 7,682,797
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7682797

Rapid classification of biological components
patent, March 2010

Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.
US Patent Document 7,682,798
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7682798

Antibody profiling sensitivity through increased reporter antibody layering
patent, April 2010

Apel, William A.; Thompson, Vicki S.
US Patent Document 7,695,919
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/7695919

Micro-array analysis system and method thereof
patent, September 2011

Bouchard, Jean-Pierre; Claveau, Fabien; Noiseux, Isabelle
US Patent Document 8,014,577
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/8014577

Antibody profiling sensitivity through increased reporter antibody layering
patent, February 2013

Apel, William A.; Thompson, Vicki S.
US Patent Document RE44,031
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/RE44031

Rapid classification of biological components
patent, October 2013

Thompson, Vicki S.; Barrett, Karen B.; Key, Diane E.
US Patent Document RE44,539
URL: https://image-ppubs.uspto.gov/dirsearch-public/print/downloadPdf/RE44539