Multiplexed microfluidic approach for nucleic acid enrichment
Abstract
A system for enhancing a nucleic acid sample may include a one pump, a denaturing chamber; a microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample, a sample collector, and tubing connecting the pump with the denaturing chamber, the hydroxyapatite chromatography device and the sample collector such that the pump may be used to move the nucleic acid sample from the denaturing chamber to the hydroxyapatite chromatography device and then to the sample collector.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1248895
- Patent Number(s):
- 9322014
- Application Number:
- 14/084,937
- Assignee:
- Sandia Corporation (Albuquerque, NM)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2013 Nov 20
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
VanderNoot, Victoria A., Langevin, Stanley Alan, Bent, Zachary, Renzi, Ronald F., Ferko, Scott M., Van De Vreugde, James L., Lane, Todd, Patel, Kamlesh, and Branda, Steven. Multiplexed microfluidic approach for nucleic acid enrichment. United States: N. p., 2016.
Web.
VanderNoot, Victoria A., Langevin, Stanley Alan, Bent, Zachary, Renzi, Ronald F., Ferko, Scott M., Van De Vreugde, James L., Lane, Todd, Patel, Kamlesh, & Branda, Steven. Multiplexed microfluidic approach for nucleic acid enrichment. United States.
VanderNoot, Victoria A., Langevin, Stanley Alan, Bent, Zachary, Renzi, Ronald F., Ferko, Scott M., Van De Vreugde, James L., Lane, Todd, Patel, Kamlesh, and Branda, Steven. Tue .
"Multiplexed microfluidic approach for nucleic acid enrichment". United States. https://www.osti.gov/servlets/purl/1248895.
@article{osti_1248895,
title = {Multiplexed microfluidic approach for nucleic acid enrichment},
author = {VanderNoot, Victoria A. and Langevin, Stanley Alan and Bent, Zachary and Renzi, Ronald F. and Ferko, Scott M. and Van De Vreugde, James L. and Lane, Todd and Patel, Kamlesh and Branda, Steven},
abstractNote = {A system for enhancing a nucleic acid sample may include a one pump, a denaturing chamber; a microfluidic hydroxyapatite chromatography device configured for performing hydroxyapatite chromatography on the nucleic acid sample, a sample collector, and tubing connecting the pump with the denaturing chamber, the hydroxyapatite chromatography device and the sample collector such that the pump may be used to move the nucleic acid sample from the denaturing chamber to the hydroxyapatite chromatography device and then to the sample collector.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 26 00:00:00 EDT 2016},
month = {Tue Apr 26 00:00:00 EDT 2016}
}
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