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Title: Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging

Abstract

Methods, compositions, systems, devices and kits are provided herein for preparing and using a nanoparticle composition and spatial frequency heterodyne imaging for visualizing cells or tissues. In various embodiments, the nanoparticle composition includes at least one of: a nanoparticle, a polymer layer, and a binding agent, such that the polymer layer coats the nanoparticle and is for example a polyethylene glycol, a polyelectrolyte, an anionic polymer, or a cationic polymer, and such that the binding agent that specifically binds the cells or the tissue. Methods, compositions, systems, devices and kits are provided for identifying potential therapeutic agents in a model using the nanoparticle composition and spatial frequency heterodyne imaging.

Inventors:
; ; ; ;
Issue Date:
Research Org.:
BROWN UNIVERSITY, Providence, RI (United States) RHODE ISLAND HOSPITAL, Providence, RI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1247995
Patent Number(s):
9316645
Application Number:
13/645,938
Assignee:
BROWN UNIVERSITY (Providence, RI) RHODE ISLAND HOSPITAL (Providence, RI)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
DOE Contract Number:  
FG02-08ER15937
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Oct 05
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES; 77 NANOSCIENCE AND NANOTECHNOLOGY

Citation Formats

Rose-Petruck, Christoph, Wands, Jack R., Rand, Danielle, Derdak, Zoltan, and Ortiz, Vivian. Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging. United States: N. p., 2016. Web.
Rose-Petruck, Christoph, Wands, Jack R., Rand, Danielle, Derdak, Zoltan, & Ortiz, Vivian. Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging. United States.
Rose-Petruck, Christoph, Wands, Jack R., Rand, Danielle, Derdak, Zoltan, and Ortiz, Vivian. Tue . "Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging". United States. https://www.osti.gov/servlets/purl/1247995.
@article{osti_1247995,
title = {Methods, compositions and kits for imaging cells and tissues using nanoparticles and spatial frequency heterodyne imaging},
author = {Rose-Petruck, Christoph and Wands, Jack R. and Rand, Danielle and Derdak, Zoltan and Ortiz, Vivian},
abstractNote = {Methods, compositions, systems, devices and kits are provided herein for preparing and using a nanoparticle composition and spatial frequency heterodyne imaging for visualizing cells or tissues. In various embodiments, the nanoparticle composition includes at least one of: a nanoparticle, a polymer layer, and a binding agent, such that the polymer layer coats the nanoparticle and is for example a polyethylene glycol, a polyelectrolyte, an anionic polymer, or a cationic polymer, and such that the binding agent that specifically binds the cells or the tissue. Methods, compositions, systems, devices and kits are provided for identifying potential therapeutic agents in a model using the nanoparticle composition and spatial frequency heterodyne imaging.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 19 00:00:00 EDT 2016},
month = {Tue Apr 19 00:00:00 EDT 2016}
}

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