Monodisperse microdroplet generation and stopping without coalescence
Abstract
A system for monodispersed microdroplet generation and trapping including providing a flow channel in a microchip; producing microdroplets in the flow channel, the microdroplets movable in the flow channel; providing carrier fluid in the flow channel using a pump or pressure source; controlling movement of the microdroplets in the flow channel and trapping the microdroplets in a desired location in the flow channel. The system includes a microchip; a flow channel in the microchip; a droplet maker that generates microdroplets, the droplet maker connected to the flow channel; a carrier fluid in the flow channel, the carrier fluid introduced to the flow channel by a source of carrier fluid, the source of carrier fluid including a pump or pressure source; a valve connected to the carrier fluid that controls flow of the carrier fluid and enables trapping of the microdroplets.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1239825
- Patent Number(s):
- 9266107
- Application Number:
- 14/662,535
- Assignee:
- Lawrence Livermore National Security, LLC (Livermore, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G05 - CONTROLLING G05D - SYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
- DOE Contract Number:
- AC52-07NA27344
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Mar 19
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION; 42 ENGINEERING; 60 APPLIED LIFE SCIENCES
Citation Formats
Beer, Neil Reginald. Monodisperse microdroplet generation and stopping without coalescence. United States: N. p., 2016.
Web.
Beer, Neil Reginald. Monodisperse microdroplet generation and stopping without coalescence. United States.
Beer, Neil Reginald. Tue .
"Monodisperse microdroplet generation and stopping without coalescence". United States. https://www.osti.gov/servlets/purl/1239825.
@article{osti_1239825,
title = {Monodisperse microdroplet generation and stopping without coalescence},
author = {Beer, Neil Reginald},
abstractNote = {A system for monodispersed microdroplet generation and trapping including providing a flow channel in a microchip; producing microdroplets in the flow channel, the microdroplets movable in the flow channel; providing carrier fluid in the flow channel using a pump or pressure source; controlling movement of the microdroplets in the flow channel and trapping the microdroplets in a desired location in the flow channel. The system includes a microchip; a flow channel in the microchip; a droplet maker that generates microdroplets, the droplet maker connected to the flow channel; a carrier fluid in the flow channel, the carrier fluid introduced to the flow channel by a source of carrier fluid, the source of carrier fluid including a pump or pressure source; a valve connected to the carrier fluid that controls flow of the carrier fluid and enables trapping of the microdroplets.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 23 00:00:00 EST 2016},
month = {Tue Feb 23 00:00:00 EST 2016}
}
Works referenced in this record:
Monodisperse droplet generation and rapid trapping for single molecule detection and reaction kinetics measurement
journal, January 2009
- Beer, Neil Reginald; Rose, Klint Aaron; Kennedy, Ian M.
- Lab Chip, Vol. 9, Issue 6
Sorting, amplification, detection, and identification of nucleic acid subsequences in a complex mixture
patent-application, July 2008
- Beer, Neil; Hindson, Benjamin; Colson, Billy
- US Patent Application 11/650363; 20080166793