Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display
Abstract
The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein. including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.
- Inventors:
- Issue Date:
- Research Org.:
- University of California, Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1176104
- Patent Number(s):
- 7176000
- Application Number:
- 10/617,012
- Assignee:
- Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- DOE Contract Number:
- FG-91ER61125
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2003 Jul 10
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Glazer, Alexander N., and Cai, Yuping. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display. United States: N. p., 2007.
Web.
Glazer, Alexander N., & Cai, Yuping. Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display. United States.
Glazer, Alexander N., and Cai, Yuping. Tue .
"Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display". United States. https://www.osti.gov/servlets/purl/1176104.
@article{osti_1176104,
title = {Multifunctional recombinant phycobiliprotein-based fluorescent constructs and phycobilisome display},
author = {Glazer, Alexander N. and Cai, Yuping},
abstractNote = {The invention provides multifunctional fusion constructs which are rapidly incorporated into a macromolecular structure such as a phycobilisome such that the fusion proteins are separated from one another and unable to self-associate. The invention provides methods and compositions for displaying a functional polypeptide domain on an oligomeric phycobiliprotein. including fusion proteins comprising a functional displayed domain and a functional phycobiliprotein domain incorporated in a functional oligomeric phycobiliprotein. The fusion proteins provide novel specific labeling reagents.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 13 00:00:00 EST 2007},
month = {Tue Feb 13 00:00:00 EST 2007}
}
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Works referenced in this record:
Recombinant Phycobiliproteins
journal, March 2001
- Cai, Yuping A.; Murphy, John T.; Wedemayer, Gary J.
- Analytical Biochemistry, Vol. 290, Issue 2
Detection of Dimers of Dimers of Human Leukocyte Antigen (HLA)–DR on the Surface of Living Cells by Single-Particle Fluorescence Imaging
journal, January 1998
- Cherry, Richard J.; Wilson, Keith M.; Triantafilou, Kathy
- Journal of Cell Biology, Vol. 140, Issue 1