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Title: DNA encoding a DNA repair protein

Abstract

An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.

Inventors:
; ; ;
Issue Date:
Research Org.:
Wisconsin Alumni Research Foundation, Madison, WI (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175872
Patent Number(s):
7091037
Application Number:
09/837,602
Assignee:
Wisconsin Alumni Research Foundation
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
4459-011502
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Petrini, John H., Morgan, William Francis, Maser, Richard Scott, and Carney, James Patrick. DNA encoding a DNA repair protein. United States: N. p., 2006. Web.
Petrini, John H., Morgan, William Francis, Maser, Richard Scott, & Carney, James Patrick. DNA encoding a DNA repair protein. United States.
Petrini, John H., Morgan, William Francis, Maser, Richard Scott, and Carney, James Patrick. Tue . "DNA encoding a DNA repair protein". United States. https://www.osti.gov/servlets/purl/1175872.
@article{osti_1175872,
title = {DNA encoding a DNA repair protein},
author = {Petrini, John H. and Morgan, William Francis and Maser, Richard Scott and Carney, James Patrick},
abstractNote = {An isolated and purified DNA molecule encoding a DNA repair protein, p95, is provided, as is isolated and purified p95. Also provided are methods of detecting p95 and DNA encoding p95. The invention further provides p95 knock-out mice.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 15 00:00:00 EDT 2006},
month = {Tue Aug 15 00:00:00 EDT 2006}
}

Works referenced in this record:

Targeting the mouse genome: a compendium of knockouts (part I)
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Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.
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Knockout Mice
journal, April 1996


Transgenic and knock-out models for studying DNA repair
journal, January 1995


hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks.
journal, October 1997


Xpaknockout mice
journal, October 1996


Deciphering the message in protein sequences: tolerance to amino acid substitutions
journal, March 1990


Targeting the mouse genome: a compendium of knockouts (part II)
journal, July 1995


Isolation and Characterization of the Human MRE11 Homologue
journal, September 1995


Nibrin, a Novel DNA Double-Strand Break Repair Protein, Is Mutated in Nijmegen Breakage Syndrome
journal, May 1998


Expression of RAD4 Gene of Saccharomyces cerevisiae That Can Be Propagated in Escherichia coli without Inactivation
journal, May 1993