DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Process for preparing a deuterated or tritiated compound

Abstract

A process for labeling organic compounds with deuterium and tritium is described using specific catalysts.

Inventors:
;
Issue Date:
Research Org.:
Univ. of California, Oakland, CA (United States); Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1175779
Patent Number(s):
7057055
Application Number:
11/243,852
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Klei, Steven R., and Bergman, Robert C. Process for preparing a deuterated or tritiated compound. United States: N. p., 2006. Web.
Klei, Steven R., & Bergman, Robert C. Process for preparing a deuterated or tritiated compound. United States.
Klei, Steven R., and Bergman, Robert C. Tue . "Process for preparing a deuterated or tritiated compound". United States. https://www.osti.gov/servlets/purl/1175779.
@article{osti_1175779,
title = {Process for preparing a deuterated or tritiated compound},
author = {Klei, Steven R. and Bergman, Robert C.},
abstractNote = {A process for labeling organic compounds with deuterium and tritium is described using specific catalysts.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 06 00:00:00 EDT 2006},
month = {Tue Jun 06 00:00:00 EDT 2006}
}

Works referenced in this record:

Electronic and Medium Effects on the Rate of Arene C−H Bond Activation by Cationic Ir(III) Complexes
journal, February 2002


Direct tritium labeling of multifunctional compounds using organoiridium catalysis. 2.
journal, August 1999


Deuteration of acetanilides and other substituted aromatics using [Ir(COD)(Cy3P)(Py)]PF6 as catalyst
journal, May 1995


Deuterium exchange labelling of substituted aromatics using [IrH2(Me2CO)2(PPh3)2]BF4
journal, May 1993


Stoichiometric and Catalytic Behavior of Cationic Silyl and Silylene Complexes
journal, October 2002


Intermediacy of an N-Heterocyclic Carbene Complex in the Catalytic C−H Activation of a Substituted Benzimidazole
journal, April 2002


Mechanism of ruthenium-catalyzed linear dimerization of acrylonitrile: a deuterium labelling study
journal, November 1983


Reactions of Cp*(PMe3)Ir(Me)OTf with Silanes:  Role of Base-Free Silylene Complexes in Rearrangements of the Resulting Silicon-Based Ligands
journal, July 2002

  • Klei, Steven R.; Tilley, T. Don; Bergman, Robert G.
  • Organometallics, Vol. 21, Issue 16, p. 3376-3387
  • URL: 10.1021/om020191+

Carbon−Carbon Bond Activation of R−CN (R = Me, Ar, i Pr, t Bu) Using a Cationic Rh(III) Complex
journal, April 2002


Synthesis and Investigation of [Cp*(PMe 3 )Rh(H)(H 2 )] + and Its Partially Deuterated and Tritiated Isotopomers:  Evidence for a Hydride/Dihydrogen Structure
journal, May 2002


Iridium-Catalyzed H/D Exchange into Organic Compounds in Water
journal, March 2002


Intermolecular Coupling of Isomerizable Alkenes to Heterocycles via Rhodium-Catalyzed C−H Bond Activation
journal, November 2002


An Examination of C−H Bond Activation by Cationic Tp Me 2 Ir(III) Complexes
journal, November 2001


Hydrogen/Deuterium Exchange Reactions and Transfer Hydrogenations Catalyzed by [C 5 Me 5 Rh(olefin) 2 ] Complexes:  Conversion of Alkoxysilanes to Silyl Enolates
journal, May 1999


Rhodium(III) and Rhodium(II) Complexes of Novel Bis(oxazoline) Pincer Ligands
journal, January 2003


Monomeric (pentamethylcyclopentadienyl)iridium imido compounds: synthesis, structure, and reactivity
journal, March 1991


Synthesis and Characterization of Hydrotris(pyrazolyl)borate Dihydrogen/Hydride Complexes of Rhodium and Iridium
journal, November 1997


Cationic Ir(III) alkyl and hydride complexes: stoichiometric and catalytic CH activation by Cp∗(PMe3)Ir(R)(X) in homogeneous solution
journal, October 2002