Passive injection control for microfluidic systems
Abstract
Apparatus for eliminating siphoning, "dead" regions, and fluid concentration gradients in microscale analytical devices. In its most basic embodiment, the present invention affords passive injection control for both electric field-driven and pressure-driven systems by providing additional fluid flow channels or auxiliary channels disposed on either side of a sample separation column. The auxiliary channels are sized such that volumetric fluid flow rate through these channels, while sufficient to move the sample away from the sample injection region in a timely fashion, is less than that through the sample separation channel or chromatograph.
- Inventors:
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-CA), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1175178
- Patent Number(s):
- 6833068
- Application Number:
- 10/341,870
- Assignee:
- Sandia National Laboratories
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01J - CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Paul, Phillip H., Arnold, Don W., and Neyer, David W. Passive injection control for microfluidic systems. United States: N. p., 2004.
Web.
Paul, Phillip H., Arnold, Don W., & Neyer, David W. Passive injection control for microfluidic systems. United States.
Paul, Phillip H., Arnold, Don W., and Neyer, David W. Tue .
"Passive injection control for microfluidic systems". United States. https://www.osti.gov/servlets/purl/1175178.
@article{osti_1175178,
title = {Passive injection control for microfluidic systems},
author = {Paul, Phillip H. and Arnold, Don W. and Neyer, David W.},
abstractNote = {Apparatus for eliminating siphoning, "dead" regions, and fluid concentration gradients in microscale analytical devices. In its most basic embodiment, the present invention affords passive injection control for both electric field-driven and pressure-driven systems by providing additional fluid flow channels or auxiliary channels disposed on either side of a sample separation column. The auxiliary channels are sized such that volumetric fluid flow rate through these channels, while sufficient to move the sample away from the sample injection region in a timely fashion, is less than that through the sample separation channel or chromatograph.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 21 00:00:00 EST 2004},
month = {Tue Dec 21 00:00:00 EST 2004}
}
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