Sample preparation and detection device for infectious agents
Abstract
A sample preparation and analysis device which incorporates both immunoassays and PCR assays in one compact, field-portable microchip. The device provides new capabilities in fluid and particle control which allows the building of a fluidic chip with no moving parts, thus decreasing fabrication cost and increasing the robustness of the device. The device can operate in a true continuous (not batch) mode. The device incorporates magnetohydrodynamic (MHD) pumps to move the fluid through the system, acoustic mixing and fractionation, dielectropheretic (DEP) sample concentration and purification, and on-chip optical detection capabilities.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174366
- Patent Number(s):
- 6576459
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 47 OTHER INSTRUMENTATION
Citation Formats
Miles, Robin R., Wang, Amy W., Fuller, Christopher K., Lemoff, Asuncion V., Bettencourt, Kerry A., and Yu, June. Sample preparation and detection device for infectious agents. United States: N. p., 2003.
Web.
Miles, Robin R., Wang, Amy W., Fuller, Christopher K., Lemoff, Asuncion V., Bettencourt, Kerry A., & Yu, June. Sample preparation and detection device for infectious agents. United States.
Miles, Robin R., Wang, Amy W., Fuller, Christopher K., Lemoff, Asuncion V., Bettencourt, Kerry A., and Yu, June. Tue .
"Sample preparation and detection device for infectious agents". United States. https://www.osti.gov/servlets/purl/1174366.
@article{osti_1174366,
title = {Sample preparation and detection device for infectious agents},
author = {Miles, Robin R. and Wang, Amy W. and Fuller, Christopher K. and Lemoff, Asuncion V. and Bettencourt, Kerry A. and Yu, June},
abstractNote = {A sample preparation and analysis device which incorporates both immunoassays and PCR assays in one compact, field-portable microchip. The device provides new capabilities in fluid and particle control which allows the building of a fluidic chip with no moving parts, thus decreasing fabrication cost and increasing the robustness of the device. The device can operate in a true continuous (not batch) mode. The device incorporates magnetohydrodynamic (MHD) pumps to move the fluid through the system, acoustic mixing and fractionation, dielectropheretic (DEP) sample concentration and purification, and on-chip optical detection capabilities.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jun 10 00:00:00 EDT 2003},
month = {Tue Jun 10 00:00:00 EDT 2003}
}
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