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Title: Variants of beta-glucosidases

Abstract

The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.

Inventors:
; ;
Issue Date:
Research Org.:
National Renewable Energy Laboratory (NREL), Golden, CO (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1160143
Patent Number(s):
8852913
Application Number:
12/639,642
Assignee:
Novozymes, Inc. (Davis, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC36-98GO10337
Resource Type:
Patent
Resource Relation:
Patent File Date: 2009 Dec 16
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Fidantsef, Ana, Lamsa, Michael, and Gorre-Clancy, Brian. Variants of beta-glucosidases. United States: N. p., 2014. Web.
Fidantsef, Ana, Lamsa, Michael, & Gorre-Clancy, Brian. Variants of beta-glucosidases. United States.
Fidantsef, Ana, Lamsa, Michael, and Gorre-Clancy, Brian. Tue . "Variants of beta-glucosidases". United States. https://www.osti.gov/servlets/purl/1160143.
@article{osti_1160143,
title = {Variants of beta-glucosidases},
author = {Fidantsef, Ana and Lamsa, Michael and Gorre-Clancy, Brian},
abstractNote = {The present invention relates to variants of a parent beta-glucosidase, comprising a substitution at one or more positions corresponding to positions 142, 183, 266, and 703 of amino acids 1 to 842 of SEQ ID NO: 2 or corresponding to positions 142, 183, 266, and 705 of amino acids 1 to 844 of SEQ ID NO: 70, wherein the variant has beta-glucosidase activity. The present invention also relates to nucleotide sequences encoding the variant beta-glucosidases and to nucleic acid constructs, vectors, and host cells comprising the nucleotide sequences.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 07 00:00:00 EDT 2014},
month = {Tue Oct 07 00:00:00 EDT 2014}
}

Works referenced in this record:

Cloning and sequencing of the cDNA encoding β-glucosidase 1 from Aspergillus aculeatus
journal, September 1996