In vivo imaging of sulfotransferases
Abstract
Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with .sup.18F, .sup.123I, .sup.124I, .sup.125I, or .sup.11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1083200
- Patent Number(s):
- 8372380
- Application Number:
- 12/594,197
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- FC02-02ER63420
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Barrio, Jorge R, Kepe, Vladimir, Small, Gary W, and Satyamurthy, Nagichettiar. In vivo imaging of sulfotransferases. United States: N. p., 2013.
Web.
Barrio, Jorge R, Kepe, Vladimir, Small, Gary W, & Satyamurthy, Nagichettiar. In vivo imaging of sulfotransferases. United States.
Barrio, Jorge R, Kepe, Vladimir, Small, Gary W, and Satyamurthy, Nagichettiar. Tue .
"In vivo imaging of sulfotransferases". United States. https://www.osti.gov/servlets/purl/1083200.
@article{osti_1083200,
title = {In vivo imaging of sulfotransferases},
author = {Barrio, Jorge R and Kepe, Vladimir and Small, Gary W and Satyamurthy, Nagichettiar},
abstractNote = {Radiolabeled tracers for sulfotransferases (SULTs), their synthesis, and their use are provided. Included are substituted phenols, naphthols, coumarins, and flavones radiolabeled with .sup.18F, .sup.123I, .sup.124I, .sup.125I, or .sup.11C. Also provided are in vivo techniques for using these and other tracers as analytical and diagnostic tools to study sulfotransferase distribution and activity, in health and disease, and to evaluate therapeutic interventions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 12 00:00:00 EST 2013},
month = {Tue Feb 12 00:00:00 EST 2013}
}
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