Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate
Abstract
Through screening of a Zymomonas mutant library the himA gene was found to be involved in the inhibitory effect of acetate on Zymomonas performance. Xylose-utilizing Zymomonas strains further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in mixed-sugars medium comprising xylose, and, in particular, in the presence of acetate.
- Inventors:
-
- Kennett Square, PA
- Lakewood, CO
- Centennial, CO
- Newark, DE
- Havertown, PA
- West Chester, PA
- New Hope, PA
- Issue Date:
- Research Org.:
- National Renewable Energy Laboratory (NREL), Golden, CO (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1016555
- Patent Number(s):
- 7897396
- Application Number:
- US Patent Application 12/261,160
- Assignee:
- E.I. du Pont de Nemours and Company (Wilmington, DE); Alliance for Sustainable Energy LLC (
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- DOE Contract Number:
- AC36-08GO28308
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Caimi, Perry G, Chou, Yat-Chen, Franden, Mary Ann, Knoke, Kyle, Tao, Luan, Viitanen, Paul V, Zhang, Min, and Zhang, Yuying. Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate. United States: N. p., 2011.
Web.
Caimi, Perry G, Chou, Yat-Chen, Franden, Mary Ann, Knoke, Kyle, Tao, Luan, Viitanen, Paul V, Zhang, Min, & Zhang, Yuying. Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate. United States.
Caimi, Perry G, Chou, Yat-Chen, Franden, Mary Ann, Knoke, Kyle, Tao, Luan, Viitanen, Paul V, Zhang, Min, and Zhang, Yuying. Tue .
"Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate". United States. https://www.osti.gov/servlets/purl/1016555.
@article{osti_1016555,
title = {Zymomonas with improved ethanol production in medium containing concentrated sugars and acetate},
author = {Caimi, Perry G and Chou, Yat-Chen and Franden, Mary Ann and Knoke, Kyle and Tao, Luan and Viitanen, Paul V and Zhang, Min and Zhang, Yuying},
abstractNote = {Through screening of a Zymomonas mutant library the himA gene was found to be involved in the inhibitory effect of acetate on Zymomonas performance. Xylose-utilizing Zymomonas strains further engineered to reduce activity of the himA gene were found to have increased ethanol production in comparison to a parental strain, when cultured in mixed-sugars medium comprising xylose, and, in particular, in the presence of acetate.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 01 00:00:00 EST 2011},
month = {Tue Mar 01 00:00:00 EST 2011}
}
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