Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof
Abstract
Compositions and methods of producing components of protein biosynthetic machinery that include glutamyl orthogonal tRNAs, glutamyl orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of glutamyl tRNAs/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.
- Inventors:
-
- San Francisco, CA
- La Jolla, CA
- Cambridge, MA
- Issue Date:
- Research Org.:
- The Scripps Research Institute (US)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 988159
- Patent Number(s):
- 7527943
- Application Number:
- 10/563,656
- Assignee:
- The Scripps Research Institute (La Jolla, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- FG03-00ER45812
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Anderson, J Christopher, Schultz, Peter G, and Santoro, Stephen. Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof. United States: N. p., 2009.
Web.
Anderson, J Christopher, Schultz, Peter G, & Santoro, Stephen. Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof. United States.
Anderson, J Christopher, Schultz, Peter G, and Santoro, Stephen. Tue .
"Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof". United States. https://www.osti.gov/servlets/purl/988159.
@article{osti_988159,
title = {Compositions of orthogonal glutamyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof},
author = {Anderson, J Christopher and Schultz, Peter G and Santoro, Stephen},
abstractNote = {Compositions and methods of producing components of protein biosynthetic machinery that include glutamyl orthogonal tRNAs, glutamyl orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of glutamyl tRNAs/synthetases are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins using these orthogonal pairs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2009},
month = {5}
}
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