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Title: Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system

Abstract

An improved method for enhancing the contrast between background and lesion areas of a breast undergoing dual-head scintimammographic examination comprising: 1) acquiring a pair of digital images from a pair of small FOV or mini gamma cameras compressing the breast under examination from opposing sides; 2) inverting one of the pair of images to align or co-register with the other of the images to obtain co-registered pixel values; 3) normalizing the pair of images pixel-by-pixel by dividing pixel values from each of the two acquired images and the co-registered image by the average count per pixel in the entire breast area of the corresponding detector; and 4) multiplying the number of counts in each pixel by the value obtained in step 3 to produce a normalization enhanced two dimensional contrast map. This enhanced (increased contrast) contrast map enhances the visibility of minor local increases (uptakes) of activity over the background and therefore improves lesion detection sensitivity, especially of small lesions.

Inventors:
 [1];  [2];  [3]
  1. Newport News, VA
  2. Yorktown, VA
  3. Hampton, VA
Issue Date:
Research Org.:
Southeastern University Research Associates
Sponsoring Org.:
USDOE
OSTI Identifier:
985168
Patent Number(s):
7444009
Application Number:
10/961,552
Assignee:
Jefferson Science Associates (Newport News, VA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01T - MEASUREMENT OF NUCLEAR OR X-RADIATION
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
DOE Contract Number:  
AC05-84ER40150
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Kieper, Douglas Arthur, Majewski, Stanislaw, and Welch, Benjamin L. Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system. United States: N. p., 2008. Web.
Kieper, Douglas Arthur, Majewski, Stanislaw, & Welch, Benjamin L. Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system. United States.
Kieper, Douglas Arthur, Majewski, Stanislaw, and Welch, Benjamin L. Tue . "Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system". United States. https://www.osti.gov/servlets/purl/985168.
@article{osti_985168,
title = {Method to improve cancerous lesion detection sensitivity in a dedicated dual-head scintimammography system},
author = {Kieper, Douglas Arthur and Majewski, Stanislaw and Welch, Benjamin L},
abstractNote = {An improved method for enhancing the contrast between background and lesion areas of a breast undergoing dual-head scintimammographic examination comprising: 1) acquiring a pair of digital images from a pair of small FOV or mini gamma cameras compressing the breast under examination from opposing sides; 2) inverting one of the pair of images to align or co-register with the other of the images to obtain co-registered pixel values; 3) normalizing the pair of images pixel-by-pixel by dividing pixel values from each of the two acquired images and the co-registered image by the average count per pixel in the entire breast area of the corresponding detector; and 4) multiplying the number of counts in each pixel by the value obtained in step 3 to produce a normalization enhanced two dimensional contrast map. This enhanced (increased contrast) contrast map enhances the visibility of minor local increases (uptakes) of activity over the background and therefore improves lesion detection sensitivity, especially of small lesions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {10}
}

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