Title: Microluminometer chip and method to measure bioluminescence

Abstract

An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on the chip for processing the photocurrent. A distributed electrode configuration including a plurality of spaced apart electrodes disposed on an active region of the photodetector is preferably used to raise efficiency.

Inventors:

Simpson, Michael L ^[1]; Paulus, Michael J ^[1]; Sayler, Gary S ^[2]; Applegate, Bruce M ^[3]; Ripp, Steven A ^[1]

---

+ Show Inventor Affiliations

1. Knoxville, TN
2. Blaine, TN
3. West Lafayette, IN

Issue Date:

Tue May 13 00:00:00 EDT 2008

Research Org.:

Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)

Sponsoring Org.:

USDOE

OSTI Identifier:

981853

Patent Number(s):

7371538

Application Number:

11/151,964

Assignee:

UT-Battelle, LLC (Oak Ridge, TN)

Patent Classifications (CPCs):

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

Show more

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

A61B5/0031 - {Implanted circuitry}

C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS

C12Q1/02 - involving viable microorganisms
C12Q1/66 - involving luciferase

G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES

G01N21/763 - {Bioluminescence}
G01N33/74 - involving hormones {or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors}
G01N33/84 - involving inorganic compounds or pH

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS

Y10S435/808 - Optical sensing apparatus
Y10S435/849 - Escherichia coli
Y10S435/879 - Salmonella
Y10S435/909 - Vibrio
Y10S436/805 - Optical property

Show less

DOE Contract Number:  

FG05-94ER61870

Resource Type:

Patent

Country of Publication:

United States

Language:

English

Subject:

47 OTHER INSTRUMENTATION