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Title: A process for the separation and purification of yttrium-90 for medical applications

Abstract

An extraction chromatographic method for the preparation of {sup 90}Y of high chemical and radiochemical purity is disclosed. After an initial purification of a {sup 90}Sr stock solution and a suitable period of {sup 90}Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the {sup 90}Sr content of the mixture by a factor of about 10{sup 3}. The {sup 90}Y remaining is freed from any residual {sup 90}Sr, from its {sup 90}Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.

Inventors:
;
Issue Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE, Washington, DC (United States)
OSTI Identifier:
97209
Patent Number(s):
8095555
Application Number:
ON: DE95017129; PAN: 8-095,555
Assignee:
ANL; SCA: 550604; 400201; PA: EDB-95:126463; NTS-96:001553; ERA-20:027650; SN: 95001445197
Patent Classifications (CPCs):
G - PHYSICS G06 - COMPUTING G06F - ELECTRIC DIGITAL DATA PROCESSING
DOE Contract Number:  
W-31-109-ENG-38
Resource Type:
Patent
Resource Relation:
Patent File Date: 1993 Jul 26; Other Information: PBD: 1993; Related Information: U. S. Patent No. 5,368,736. Filed 11/29/1994.
Country of Publication:
United States
Language:
English
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; 40 CHEMISTRY; YTTRIUM 90; CHEMICAL PREPARATION; INVENTIONS; DESIGN; PURIFICATION; STRONTIUM 90; EXTRACTION; RADIOTHERAPY

Citation Formats

Horwitz, P E, and Dietz, M L. A process for the separation and purification of yttrium-90 for medical applications. United States: N. p., 1993. Web.
Horwitz, P E, & Dietz, M L. A process for the separation and purification of yttrium-90 for medical applications. United States.
Horwitz, P E, and Dietz, M L. Fri . "A process for the separation and purification of yttrium-90 for medical applications". United States. https://www.osti.gov/servlets/purl/97209.
@article{osti_97209,
title = {A process for the separation and purification of yttrium-90 for medical applications},
author = {Horwitz, P E and Dietz, M L},
abstractNote = {An extraction chromatographic method for the preparation of {sup 90}Y of high chemical and radiochemical purity is disclosed. After an initial purification of a {sup 90}Sr stock solution and a suitable period of {sup 90}Y ingrowth, the solution is passed through a series of strontium-selective chromatographic columns, each of which lowers the {sup 90}Sr content of the mixture by a factor of about 10{sup 3}. The {sup 90}Y remaining is freed from any residual {sup 90}Sr, from its {sup 90}Zr daughter, and from any remaining impurities by passing the sample through a final column designed to selectively retain yttrium.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1993},
month = {1}
}