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Title: Methods and devices for protein assays

Abstract

Methods and devices for protein assays based on Edman degradation in microfluidic channels are disclosed herein. As disclosed, the cleaved amino acid residues may be immobilized in an array format and identified by detectable labels, such as antibodies, which specifically bind given amino acid residues. Alternatively, the antibodies are immobilized in an array format and the cleaved amino acids are labeled identified by being bound by the antibodies in the array.

Inventors:
 [1];  [2];  [3]
  1. San Jose, CA
  2. Indianapolis, IN
  3. Oakland, CA
Issue Date:
Research Org.:
Sandia National Laboratories (SNL-CA), Livermore, CA
Sponsoring Org.:
USDOE
OSTI Identifier:
971528
Patent Number(s):
7,611,834
Application Number:
11/239,387
Assignee:
Sandia Corporation (Livermore, CA)
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Chhabra, Swapnil, Cintron, Jose M, and Shediac, Renee. Methods and devices for protein assays. United States: N. p., 2009. Web.
Chhabra, Swapnil, Cintron, Jose M, & Shediac, Renee. Methods and devices for protein assays. United States.
Chhabra, Swapnil, Cintron, Jose M, and Shediac, Renee. Tue . "Methods and devices for protein assays". United States. https://www.osti.gov/servlets/purl/971528.
@article{osti_971528,
title = {Methods and devices for protein assays},
author = {Chhabra, Swapnil and Cintron, Jose M and Shediac, Renee},
abstractNote = {Methods and devices for protein assays based on Edman degradation in microfluidic channels are disclosed herein. As disclosed, the cleaved amino acid residues may be immobilized in an array format and identified by detectable labels, such as antibodies, which specifically bind given amino acid residues. Alternatively, the antibodies are immobilized in an array format and the cleaved amino acids are labeled identified by being bound by the antibodies in the array.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2009},
month = {11}
}

Patent:

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