Methods and devices for protein assays
Abstract
Methods and devices for protein assays based on Edman degradation in microfluidic channels are disclosed herein. As disclosed, the cleaved amino acid residues may be immobilized in an array format and identified by detectable labels, such as antibodies, which specifically bind given amino acid residues. Alternatively, the antibodies are immobilized in an array format and the cleaved amino acids are labeled identified by being bound by the antibodies in the array.
- Inventors:
-
- San Jose, CA
- Indianapolis, IN
- Oakland, CA
- Issue Date:
- Research Org.:
- Sandia National Lab. (SNL-CA), Livermore, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 971528
- Patent Number(s):
- 7611834
- Application Number:
- 11/239,387
- Assignee:
- Sandia Corporation (Livermore, CA)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Chhabra, Swapnil, Cintron, Jose M, and Shediac, Renee. Methods and devices for protein assays. United States: N. p., 2009.
Web.
Chhabra, Swapnil, Cintron, Jose M, & Shediac, Renee. Methods and devices for protein assays. United States.
Chhabra, Swapnil, Cintron, Jose M, and Shediac, Renee. Tue .
"Methods and devices for protein assays". United States. https://www.osti.gov/servlets/purl/971528.
@article{osti_971528,
title = {Methods and devices for protein assays},
author = {Chhabra, Swapnil and Cintron, Jose M and Shediac, Renee},
abstractNote = {Methods and devices for protein assays based on Edman degradation in microfluidic channels are disclosed herein. As disclosed, the cleaved amino acid residues may be immobilized in an array format and identified by detectable labels, such as antibodies, which specifically bind given amino acid residues. Alternatively, the antibodies are immobilized in an array format and the cleaved amino acids are labeled identified by being bound by the antibodies in the array.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 03 00:00:00 EST 2009},
month = {Tue Nov 03 00:00:00 EST 2009}
}