skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Sleeve reaction chamber system

Abstract

A chemical reaction chamber system that combines devices such as doped polysilicon for heating, bulk silicon for convective cooling, and thermoelectric (TE) coolers to augment the heating and cooling rates of the reaction chamber or chambers. In addition the system includes non-silicon-based reaction chambers such as any high thermal conductivity material used in combination with a thermoelectric cooling mechanism (i.e., Peltier device). The heat contained in the thermally conductive part of the system can be used/reused to heat the device, thereby conserving energy and expediting the heating/cooling rates. The system combines a micromachined silicon reaction chamber, for example, with an additional module/device for augmented heating/cooling using the Peltier effect. This additional module is particularly useful in extreme environments (very hot or extremely cold) where augmented heating/cooling would be useful to speed up the thermal cycling rates. The chemical reaction chamber system has various applications for synthesis or processing of organic, inorganic, or biochemical reactions, including the polymerase chain reaction (PCR) and/or other DNA reactions, such as the ligase chain reaction.

Inventors:
 [1];  [2];  [3];  [4];  [3];  [3];  [5]
  1. Berkeley, CA
  2. San Mateo, CA
  3. Livermore, CA
  4. Manteca, CA
  5. Pleasanton, CA
Issue Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
968326
Patent Number(s):
7578976
Application Number:
09/568,618
Assignee:
OAK
Patent Classifications (CPCs):
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats

Northrup, M Allen, Beeman, Barton V, Benett, William J, Hadley, Dean R, Landre, Phoebe, Lehew, Stacy L, and Krulevitch, Peter A. Sleeve reaction chamber system. United States: N. p., 2009. Web.
Northrup, M Allen, Beeman, Barton V, Benett, William J, Hadley, Dean R, Landre, Phoebe, Lehew, Stacy L, & Krulevitch, Peter A. Sleeve reaction chamber system. United States.
Northrup, M Allen, Beeman, Barton V, Benett, William J, Hadley, Dean R, Landre, Phoebe, Lehew, Stacy L, and Krulevitch, Peter A. Tue . "Sleeve reaction chamber system". United States. https://www.osti.gov/servlets/purl/968326.
@article{osti_968326,
title = {Sleeve reaction chamber system},
author = {Northrup, M Allen and Beeman, Barton V and Benett, William J and Hadley, Dean R and Landre, Phoebe and Lehew, Stacy L and Krulevitch, Peter A},
abstractNote = {A chemical reaction chamber system that combines devices such as doped polysilicon for heating, bulk silicon for convective cooling, and thermoelectric (TE) coolers to augment the heating and cooling rates of the reaction chamber or chambers. In addition the system includes non-silicon-based reaction chambers such as any high thermal conductivity material used in combination with a thermoelectric cooling mechanism (i.e., Peltier device). The heat contained in the thermally conductive part of the system can be used/reused to heat the device, thereby conserving energy and expediting the heating/cooling rates. The system combines a micromachined silicon reaction chamber, for example, with an additional module/device for augmented heating/cooling using the Peltier effect. This additional module is particularly useful in extreme environments (very hot or extremely cold) where augmented heating/cooling would be useful to speed up the thermal cycling rates. The chemical reaction chamber system has various applications for synthesis or processing of organic, inorganic, or biochemical reactions, including the polymerase chain reaction (PCR) and/or other DNA reactions, such as the ligase chain reaction.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2009},
month = {8}
}

Patent:

Save / Share: