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Title: Ion funnel with extended mass range and reduced conductance limit aperture

Abstract

An improved ion funnel design is disclosed that decreases the axial RF (parasite) fields at the ion funnel exit. This is achieved by addition of one or more compensation electrodes after the conductance limit electrode. Various RF voltage profiles may be applied to the various electrodes minimizing the parasite axial potential wells. The smallest RF aperture that serves as the conductance limiting electrode is further reduced over standard designs. Overall, the ion funnel improves transmission ranges of both low m/z and high m/z ions, reducing RF activation of ions and decreasing the gas load to subsequent differential pumping stages.

Inventors:
 [1];  [1]
  1. Richland, WA
Issue Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
936229
Patent Number(s):
7351964
Application Number:
11/251,528
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
DOE Contract Number:  
AC06-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Tolmachev, Aleksey V, and Smith, Richard D. Ion funnel with extended mass range and reduced conductance limit aperture. United States: N. p., 2008. Web.
Tolmachev, Aleksey V, & Smith, Richard D. Ion funnel with extended mass range and reduced conductance limit aperture. United States.
Tolmachev, Aleksey V, and Smith, Richard D. Tue . "Ion funnel with extended mass range and reduced conductance limit aperture". United States. https://www.osti.gov/servlets/purl/936229.
@article{osti_936229,
title = {Ion funnel with extended mass range and reduced conductance limit aperture},
author = {Tolmachev, Aleksey V and Smith, Richard D},
abstractNote = {An improved ion funnel design is disclosed that decreases the axial RF (parasite) fields at the ion funnel exit. This is achieved by addition of one or more compensation electrodes after the conductance limit electrode. Various RF voltage profiles may be applied to the various electrodes minimizing the parasite axial potential wells. The smallest RF aperture that serves as the conductance limiting electrode is further reduced over standard designs. Overall, the ion funnel improves transmission ranges of both low m/z and high m/z ions, reducing RF activation of ions and decreasing the gas load to subsequent differential pumping stages.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {4}
}

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Works referenced in this record:

An Ion Funnel Interface for Improved Ion Focusing and Sensitivity Using Electrospray Ionization Mass Spectrometry
journal, October 1998


High-Sensitivity Ion Mobility Spectrometry/Mass Spectrometry Using Electrodynamic Ion Funnel Interfaces
journal, May 2005


Characterization of an Improved Electrodynamic Ion Funnel Interface for Electrospray Ionization Mass Spectrometry
journal, August 1999


Simulation-based optimization of the electrodynamic ion funnel for high sensitivity electrospray ionization mass spectrometry
journal, December 2000